Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 3/20 | 0.38 |
| ▸ | PTPN7 | P35236 | 4/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL313412 | 0.80 | OPRM1 (0.44) | OPRM1 | |
| SCHEMBL3532757 | 0.80 | OPRM1 (0.44) | OPRM1 | |
| SCHEMBL30572137 | 0.80 | OPRM1 (0.44) | OPRM1 | |
| SCHEMBL28842995 | 0.80 | OPRM1 (0.44) | OPRM1 | |
| SCHEMBL30537662 | 0.80 | OPRM1 (0.44) | OPRM1 | |
| SCHEMBL60064 | 0.80 | HMGCR (0.40) | HMGCRPTPN7 | |
| SCHEMBL11580737 | 0.78 | — | — | |
| SCHEMBL8649300 | 0.78 | HMGCR (0.38) | HMGCRPTPN7 | |
| SCHEMBL7122689 | 0.77 | DNM1 (0.42) | HMGCRPTPN7 | |
| SCHEMBL60156 | 0.75 | HMGCR (0.35) | HMGCRPTPN7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2545923-A1 | Antibacterial agents | Alchemia Limited (AU) | 2013-01-16 | — | — | EP | disclosed |
| EP-1934388-B1 | METHOD OF DRUG DESIGN | ALCHEMIA LTD (AU) | 2012-12-05 | — | — | EP | disclosed |
| EP-1962864-A1 | ANTIBACTERIAL AGENTS | Alchemia Limited (AU) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007070947-A1 | ANTIBACTERIAL AGENTS | ALCHEMIA LTD (AU) | 2007-06-28 | — | — | WO | disclosed |
| EP-1797428-A1 | SELECTIVE INHIBITORS | Alchemia Pty Ltd (AU) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006037159-A1 | SELECTIVE INHIBITORS | ALCHEMIA LIMITED (AU) | 2006-04-13 | — | — | WO | disclosed |