SCHEMBL5078713

SCHEMBL5078713

CCc1cc(C)cc(CC)c1-c1c(O)n2n(c1=O)CCOCC2

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HSD17B10 Q99714 2/20 0.38
▸ MEN1 O00255 2/20 0.38
▸ KMT2A Q03164 2/20 0.38
▸ ATM Q13315 1/20 0.38
▸ NPSR1 Q6W5P4 1/20 0.38
▸ MAPT P10636 3/20 0.36
▸ ALDH1A1 P00352 2/20 0.36
▸ MAPK1 P28482 2/20 0.36
▸ TP53 P04637 2/20 0.34
▸ LMNA P02545 4/20 0.34
▸ RAB9A P51151 1/20 0.34
▸ HTT P42858 3/20 0.33
▸ POLB P06746 2/20 0.33
▸ SMN1; SMN2 Q16637 2/20 0.33
▸ CYP3A4 P08684 1/20 0.32
▸ HPGD P15428 2/20 0.32
▸ GAA P10253 1/20 0.32
▸ PPARG P37231 1/20 0.32
▸ MAPK10 P53779 1/20 0.32
▸ NCOA2 Q15596 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1721040 0.88 LMNA (0.34) HSD17B10MEN1KMT2AMAPTALDH1A1
SCHEMBL13527337 0.81 KDM4E (0.34) HSD17B10MEN1KMT2ANPSR1MAPT
SCHEMBL24643264 0.80 MAPT (0.34) KMT2AMAPTALDH1A1MAPK1TP53
SCHEMBL13002856 0.80 ABL1 (0.34) MEN1KMT2ANPSR1MAPTALDH1A1
SCHEMBL24213873 0.78 ALDH1A1 (0.33) MEN1KMT2AMAPTALDH1A1MAPK1
SCHEMBL14088267 0.77 SYK (0.33) HSD17B10MEN1KMT2AATMNPSR1
Pinoxaden SCHEMBL29359629 0.77 ELANE (0.33) MEN1KMT2AMAPTALDH1A1MAPK1
Pinoxaden SCHEMBL64416 0.77 ELANE (0.33) MEN1KMT2AMAPTALDH1A1MAPK1
SCHEMBL1685478 0.77 KDM4E (0.39) MEN1KMT2AMAPTALDH1A1MAPK1
SCHEMBL22940089 0.76 MEN1 (0.30) HSD17B10MEN1KMT2AATMNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1605758-B1 HERBICIDAL MIXTURES BASED ON 3-PHENYLURACILS BASF SE (DE) 2008-09-10 — — EP claimed
US-20060293187-A1 Herbicidal mixtures based on 3-phenyluracils BASF AKTIENGESELLSCHAFT (DE) 2006-12-28 — — US claimed
US-20060154823-A1 Synergistically acting herbicidal mixtures BASF AKTIENGESELLSCHAFT (DE) 2006-07-13 — — US claimed
EP-1605760-A2 SYNERGISTICALLY ACTING HERBICIDAL MIXTURES BASF AKTIENGESELLSCHAFT (DE) 2005-12-21 — — EP claimed
WO-2004080171-A2 SYNERGISTICALLY ACTING HERBICIDAL MIXTURES BASF AKTIENGESELLSCHAFT (DE) 2004-09-23 — — WO claimed
EP-1053263-B1 CATALYST SYSTEM BASELL POLYOLEFINE GMBH (DE) 2003-10-01 — — EP claimed
WO-2022123541-A1 A PROCESS FOR THE PREPARATION OF PYRAZOLE-OXADIAZEPINE GHARDA CHEMICALS LIMITED (IN) 2022-06-16 — — WO disclosed
EP-1605758-B1 HERBICIDAL MIXTURES BASED ON 3-PHENYLURACILS BASF SE (DE) 2008-09-10 — — EP disclosed
US-20060293187-A1 Herbicidal mixtures based on 3-phenyluracils BASF AKTIENGESELLSCHAFT (DE) 2006-12-28 — — US disclosed
US-20060154823-A1 Synergistically acting herbicidal mixtures BASF AKTIENGESELLSCHAFT (DE) 2006-07-13 — — US disclosed
US-20060154823-A1 Synergistically acting herbicidal mixtures BASF AKTIENGESELLSCHAFT (DE) 2006-07-13 — — US disclosed
EP-1605760-A2 SYNERGISTICALLY ACTING HERBICIDAL MIXTURES BASF AKTIENGESELLSCHAFT (DE) 2005-12-21 — — EP disclosed
EP-1605760-A2 SYNERGISTICALLY ACTING HERBICIDAL MIXTURES BASF AKTIENGESELLSCHAFT (DE) 2005-12-21 — — EP disclosed
EP-1272532-B1 SALINE CHEMICAL COMPOSITION, METHOD FOR PRODUCING THE SAME AND THE USE THEREOF IN CATALYST SYSTEMS FOR PRODUCING POLYOLEFINS BASELL POLYOLEFINE GMBH (DE) 2005-05-04 — — EP disclosed
WO-2004080171-A3 SYNERGISTICALLY ACTING HERBICIDAL MIXTURES BASF AG (DE) 2005-02-10 — — WO disclosed
WO-2004080171-A2 SYNERGISTICALLY ACTING HERBICIDAL MIXTURES BASF AKTIENGESELLSCHAFT (DE) 2004-09-23 — — WO disclosed
WO-2004080171-A2 SYNERGISTICALLY ACTING HERBICIDAL MIXTURES BASF AKTIENGESELLSCHAFT (DE) 2004-09-23 — — WO disclosed
EP-1175262-B1 CATALYST SYSTEM BASELL POLYOLEFINE GMBH (DE) 2004-02-18 — — EP disclosed
EP-1053263-B1 CATALYST SYSTEM BASELL POLYOLEFINE GMBH (DE) 2003-10-01 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060293187-A1 Herbicidal mixtures based on 3-phenyluracils CBR3, CYP2W1, DDT HSD17B10 140/4885MEN1 4051/4885KMT2A 1431/4885
US-20060154823-A1 Synergistically acting herbicidal mixtures DDT, DBH, INMT HSD17B10 2895/4885MEN1 4451/4885KMT2A 430/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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