Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 5/20 | 0.45 |
| ▸ | HTR2C | P28335 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5165673 | 0.85 | KDM4E (0.57) | KDM4EALDH1A1HPGDLMNAMEN1 | |
| SCHEMBL29093412 | 0.81 | KDM4E (0.48) | KDM4EALDH1A1HPGDLMNAMEN1 | |
| SCHEMBL11805134 | 0.79 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDLMNAMEN1 | |
| SCHEMBL13101720 | 0.79 | ALDH1A1 (0.53) | KDM4EALDH1A1HPGDLMNAMEN1 | |
| SCHEMBL31365970 | 0.77 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDLMNAMEN1 | |
| SCHEMBL5376065 | 0.77 | ALDH1A1 (0.53) | KDM4EALDH1A1HPGDLMNAMEN1 | |
| SCHEMBL11809625 | 0.76 | ALDH1A1 (0.48) | KDM4EALDH1A1HPGDLMNAMEN1 | |
| SCHEMBL7825857 | 0.76 | MEN1 (0.49) | KDM4EALDH1A1HPGDLMNAMEN1 | |
| SCHEMBL18826311 | 0.73 | KDM4E (0.47) | KDM4EALDH1A1HPGDLMNAMEN1 | |
| SCHEMBL4813288 | 0.73 | LMNA (0.49) | KDM4EALDH1A1HPGDLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1608377-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING INHIBITORS OF FAB I AND FURTHER ANTIBIOTICS | AFFINIUM PHARM INC (CA) | 2008-10-01 | — | — | EP | disclosed |