Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.61 |
| ▸ | RELA | Q04206 | 1/20 | 0.61 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | KIT | P10721 | 2/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.45 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.41 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.39 |
| ▸ | STAT3 | P40763 | 2/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.36 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL460244 | 0.91 | NFKB1 (0.58) | NFKB1NFKB2RELAHTR2CKIT | |
| SCHEMBL5262815 | 0.80 | NFKB1 (0.52) | NFKB1NFKB2RELAHTR2CKIT | |
| SCHEMBL13908867 | 0.78 | NFKB1 (0.81) | NFKB1NFKB2RELAHTR2CKIT | |
| SCHEMBL2139370 | 0.77 | NFKB1 (1.00) | NFKB1NFKB2RELAHTR2CKIT | |
| SCHEMBL2136321 | 0.77 | NFKB1 (0.89) | NFKB1NFKB2RELAHTR2CKIT | |
| SCHEMBL2139019 | 0.77 | NFKB1 (0.59) | NFKB1NFKB2RELAHTR2CKIT | |
| SCHEMBL14050931 | 0.76 | NFKB1 (0.67) | NFKB1NFKB2RELAHTR2CKIT | |
| SCHEMBL16766424 | 0.76 | NFKB1 (0.70) | NFKB1NFKB2RELAHTR2CKIT | |
| SCHEMBL23579666 | 0.75 | ADRB2 (0.57) | NFKB1NFKB2RELAHTR2CKIT | |
| SCHEMBL2139575 | 0.74 | NFKB1 (0.87) | NFKB1NFKB2RELAHTR2CKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1977759-A1 | Pharmaceutical composition comprising a cytokine | 4SC AG (DE) | 2008-10-08 | — | — | EP | disclosed |