Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | BLM | P54132 | 3/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | MPO | P05164 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26693345 | 1.00 | KMT2A (0.51) | KMT2AKDM4ELMNAMAPTBLM | |
| SCHEMBL30678179 | 1.00 | KMT2A (0.51) | KMT2AKDM4ELMNAMAPTBLM | |
| SCHEMBL19911037 | 0.86 | TNF (0.58) | KMT2AKDM4ELMNAMAPTBLM | |
| SCHEMBL21315702 | 0.86 | TNF (0.58) | KMT2AKDM4ELMNAMAPTBLM | |
| SCHEMBL31675799 | 0.82 | PTPRA (0.55) | KMT2AKDM4ELMNAMAPTBLM | |
| SCHEMBL1594831 | 0.81 | MAPT (0.62) | KMT2AKDM4ELMNAMAPTBLM | |
| SCHEMBL1594834 | 0.81 | MAPT (0.62) | KMT2AKDM4ELMNAMAPTBLM | |
| SCHEMBL18029211 | 0.81 | MAPT (0.62) | KMT2AKDM4ELMNAMAPTBLM | |
| SCHEMBL7417937 | 0.78 | KMT2A (0.51) | KMT2AKDM4ELMNAMAPTBLM | |
| SCHEMBL7417940 | 0.78 | KMT2A (0.51) | KMT2AKDM4ELMNAMAPTBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250354108-A1 | METHODS FOR PRODUCING MONOTERPENE INDOLE ALKALOIDS | UNIV DANMARKS TEKNISKE (DK) | 2025-11-20 | — | — | US | disclosed |
| EP-4526426-A2 | METHODS FOR PRODUCING MONOTERPENE INDOLE ALKALOIDS | Danmarks Tekniske Universitet (DK) | 2025-03-26 | — | — | EP | disclosed |
| WO-2023222879-A2 | METHODS FOR PRODUCING MONOTERPENE INDOLE ALKALOIDS | DANMARKS TEKNISKE UNIVERSITET (DK) | 2023-11-23 | — | — | WO | disclosed |
| US-20080096870-A1 | Methods and Materials for Treating Mental Illness | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2008-04-24 | — | — | US | disclosed |
| EP-1778211-A1 | METHODS AND MATERIALS FOR TREATING MENTAL ILLNESS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006020171-A1 | METHODS AND MATERIALS FOR TREATING MENTAL ILLNESS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2006-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250354108-A1 | METHODS FOR PRODUCING MONOTERPENE INDOLE ALKALOIDS | INMT, KARS1, MIA3 | KMT2A 445/4885KDM4E 2243/4885LMNA 1953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.