Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | TLR4 | O00206 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11803300 | 0.75 | CHRM2 (0.35) | CHRM2CHRM1CHRM4CHRM3TLR4 | |
| SCHEMBL11801132 | 0.74 | METAP2 (0.38) | CHRM2CHRM1CHRM4CHRM3TLR4 | |
| SCHEMBL3676451 | 0.73 | AKR1C4 (0.54) | — | |
| SCHEMBL3127765 | 0.73 | PRKCA (0.46) | TLR4 | |
| SCHEMBL3676689 | 0.73 | AKR1C4 (0.32) | KMT2A | |
| SCHEMBL29068788 | 0.73 | PRKCA (0.46) | TLR4 | |
| SCHEMBL3678426 | 0.73 | AKR1C4 (0.54) | — | |
| SCHEMBL8516209 | 0.73 | PRKCA (0.46) | TLR4 | |
| SCHEMBL2480706 | 0.72 | THRB (0.40) | TLR4MEN1KMT2A | |
| SCHEMBL2479884 | 0.72 | THRB (0.40) | TLR4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948584-A2 | PROCESS FOR THE PREPARATION OF CYCLOPENTANONE DERIVATIVES | Firmenich SA (CH) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007056129-A2 | PROCESS FOR THE PREPARATION OF CYCLOPENTANONE DERIVATIVES | FIRMENICH SA (CH) | 2007-05-18 | — | — | WO | disclosed |