Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5074556 | 0.92 | HTT (0.41) | HTTPOLBALOX15MRGPRX4RAB9A | |
| SCHEMBL5076499 | 0.90 | ALDH1A1 (0.42) | HTTPOLBMRGPRX4RAB9ANR4A2 | |
| SCHEMBL5075845 | 0.86 | HIF1A (0.47) | HTTMRGPRX4RAB9ANPC1TP53 | |
| SCHEMBL5080347 | 0.84 | PDCD1 (0.40) | MRGPRX4RAB9ANR4A2NPC1MAOA | |
| SCHEMBL6150397 | 0.84 | HIF1A (0.50) | HTTPOLBALOX15MRGPRX4RAB9A | |
| SCHEMBL6150401 | 0.84 | HIF1A (0.50) | HTTPOLBALOX15MRGPRX4RAB9A | |
| SCHEMBL5077240 | 0.83 | HIF1A (0.44) | POLBMRGPRX4RAB9ANPC1HIF1A | |
| SCHEMBL5080427 | 0.83 | MRGPRX4 (0.38) | HTTMRGPRX4RAB9ANR4A2NPC1 | |
| SCHEMBL6150598 | 0.83 | MRGPRX4 (0.38) | HTTMRGPRX4RAB9ANR4A2NPC1 | |
| SCHEMBL6157649 | 0.83 | HTT (0.39) | HTTPOLBALOX15MRGPRX4RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7435844-B2 | Analogous compounds of strobilurines and their use as acaricides and insecticides | ISAGRO RICERCA S.R.L. (IT) | 2008-10-14 | — | — | US | disclosed |
| US-20060235075-A1 | Analogous compounds of strobilurines and their use as acaricides and insecticides | ISAGRO RICERCA S.R.L. (IT) | 2006-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060235075-A1 | Analogous compounds of strobilurines and their use as acaricides and insecticides | DDT, RYR1, TPMT | HTT 4420/4885POLB 4745/4885ALOX15 3972/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.