SCHEMBL5080373

SCHEMBL5080373

C/C=C(/C(=O)O)c1ccccc1COc1cc(Cl)c(OCCOC)c(Cl)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.40
TP53 P04637 1/20 0.40
MRGPRX4 Q96LA9 2/20 0.40
RAB9A P51151 2/20 0.39
MEN1 O00255 2/20 0.39
ALDH1A1 P00352 2/20 0.39
LMNA P02545 2/20 0.39
HPGD P15428 2/20 0.39
KMT2A Q03164 2/20 0.39
ABL1 P00519 1/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
RIN1 Q13671 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NR4A2 P43354 2/20 0.38
NPC1 O15118 1/20 0.38
PTPRC P08575 1/20 0.37
PTPN1 P18031 1/20 0.37
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5080368 0.92 TP53 (0.39) HTTTP53MRGPRX4RAB9AMEN1
SCHEMBL5080378 0.92 TP53 (0.39) HTTTP53MRGPRX4RAB9AMEN1
SCHEMBL5080507 0.90 TP53 (0.41) HTTTP53MRGPRX4RAB9AMEN1
SCHEMBL5080519 0.89 ALDH1A1 (0.40) HTTTP53MRGPRX4RAB9AMEN1
SCHEMBL5079483 0.89 MRGPRX4 (0.46) HTTTP53MRGPRX4RAB9AMEN1
SCHEMBL5075977 0.88 RAB9A (0.48) HTTTP53MRGPRX4RAB9AMEN1
SCHEMBL5074570 0.87 PTPN11 (0.42) HTTTP53MRGPRX4RAB9AMEN1
SCHEMBL5074562 0.87 TP53 (0.39) HTTTP53MRGPRX4RAB9AMEN1
SCHEMBL5075946 0.87 THRA (0.40) HTTTP53MRGPRX4RAB9AMEN1
SCHEMBL5079564 0.87 PTPN11 (0.42) HTTTP53MRGPRX4RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7435844-B2 Analogous compounds of strobilurines and their use as acaricides and insecticides ISAGRO RICERCA S.R.L. (IT) 2008-10-14 US disclosed
US-20060235075-A1 Analogous compounds of strobilurines and their use as acaricides and insecticides ISAGRO RICERCA S.R.L. (IT) 2006-10-19 US disclosed
EP-1494991-A1 ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES Isagro Ricerca S.r.l. (IT) 2005-01-12 EP disclosed
WO-2003087032-A1 ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES ISAGRO RICERCA S.R.L. (IT) 2003-10-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060235075-A1 Analogous compounds of strobilurines and their use as acaricides and insecticides DDT, RYR1, TPMT HTT 4420/4885TP53 2842/4885MRGPRX4 989/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.