SCHEMBL50808

SCHEMBL50808

O=C(O)c1ccc(OC(Cc2ccccc2)c2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 3/20 0.56
NR4A1 P22736 1/20 0.53
NR4A2 P43354 1/20 0.53
NR4A3 Q92570 1/20 0.53
PPARG P37231 13/20 0.51
PPARA Q07869 11/20 0.51
KMT2A Q03164 1/20 0.49
PKM P14618 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1908115 0.87 SLC6A4 (0.49) PPARGPPARA
SCHEMBL7324696 0.85 F2 (0.54) SRD5A2NR4A1NR4A2NR4A3PPARG
SCHEMBL8332028 0.83 AKR1B1 (0.52) SRD5A2PPARGPPARA
SCHEMBL6566061 0.83 SLC6A4 (0.53) PPARGPPARA
SCHEMBL13951751 0.83 SRD5A2 (0.58) SRD5A2NR4A1NR4A2NR4A3KMT2A
SCHEMBL1096056 0.83 ESR1 (0.49) SRD5A2NR4A1NR4A2NR4A3KMT2A
SCHEMBL7324691 0.82 NR4A1 (0.57) SRD5A2NR4A1NR4A2NR4A3PPARG
SCHEMBL28489137 0.82 ALDH1A1 (0.51) PPARGPPARA
SCHEMBL9713215 0.80 SRD5A2 (0.55) SRD5A2KMT2APKM
SCHEMBL6259034 0.80 SRD5A2 (0.55) SRD5A2NR4A1NR4A2NR4A3KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3352991-A1 HEAT-SENSITIVE RECORDING MATERIAL Mitsubishi HiTec Paper Europe GmbH (DE) 2018-08-01 EP claimed
CN-117881546-A Thermal recording material, method of decolorizing thermal recording material, fiber material mixture, method for producing recycled paper, and recycled paper 科勒创新科技有限公司 2024-04-12 CN disclosed
US-11926168-B2 Non-phenolic color developer and heat-sensitive recording material PAPIERFABRIK AUGUST KOEHLER SE (DE) 2024-03-12 US disclosed
CN-117500672-A Thermosensitive recording material 科勒创新科技有限公司 2024-02-02 CN disclosed
CN-114746279-B Polymorphic forms of N- (4- ((4- (3-phenylureido) phenyl) sulfonyl) phenyl) benzenesulfonamide and preparation method thereof 科勒造纸欧洲股份公司 2023-11-03 CN disclosed
US-11084307-B2 Heat-sensitive recording material PAPIERFABRIK AUGUST KOEHLER SE (DE) 2021-08-10 US disclosed
US-20200172477-A1 NON-PHENOLIC COLOR DEVELOPER AND HEAT-SENSITIVE RECORDING MATERIAL PAPIERFABRIK AUGUST KOEHLER SE (DE) 2020-06-04 US disclosed
US-20200070556-A1 HEAT-SENSITIVE RECORDING MATERIAL PAPIERFABRIK AUGUST KOEHLER SE (DE) 2020-03-05 US disclosed
US-8129307-B2 Thermosensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2012-03-06 US disclosed
EP-2112001-B1 THERMOSENSITIVE RECORDING MEDIUM JUJO PAPER CO LTD (JP) 2011-05-11 EP disclosed
US-20100099557-A1 Thermosensitive Recording Medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2010-04-22 US disclosed
EP-2112001-A1 THERMAL RECORDING MATERIAL Nippon Paper Industries CO., LTD. (JP) 2009-10-28 EP disclosed
US-20090082202-A1 Heat-sensitive recording material MITSUBISHI HITEC PAPER FLENSBURG GMBH 2009-03-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11084307-B2 Heat-sensitive recording material SCN2B, SCN1B, SCN1A SRD5A2 303/4885NR4A1 176/4885NR4A2 114/4885
US-20200172477-A1 NON-PHENOLIC COLOR DEVELOPER AND HEAT-SENSITIVE RECORDING MATERIAL TDO2, SCO2, SCN1A SRD5A2 66/4885NR4A1 124/4885NR4A2 99/4885
US-11926168-B2 Non-phenolic color developer and heat-sensitive recording material TDO2, SCO2, SCN1A SRD5A2 63/4885NR4A1 123/4885NR4A2 97/4885
US-20200070556-A1 HEAT-SENSITIVE RECORDING MATERIAL SCN1B, SCN1A, SCN2B SRD5A2 305/4885NR4A1 144/4885NR4A2 96/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.