SCHEMBL6566061

SCHEMBL6566061

c1ccc(CC(Oc2ccccc2)c2ccccc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 8/20 0.53
PPARG P37231 6/20 0.46
PPARA Q07869 6/20 0.46
SLC6A2 P23975 3/20 0.42
SLC6A3 Q01959 3/20 0.42
KCNK2 O95069 1/20 0.42
KCNH2 Q12809 1/20 0.42
CACNA1C Q13936 1/20 0.42
F2 P00734 1/20 0.42
PRSS1 P07477 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1908115 0.96 SLC6A4 (0.49) SLC6A4PPARGPPARASLC6A2SLC6A3
SCHEMBL11838145 0.87 SLC6A4 (0.46) SLC6A4PPARGPPARASLC6A2SLC6A3
SCHEMBL11844149 0.86 PPARG (0.55) SLC6A4PPARGPPARAF2PRSS1
SCHEMBL28788669 0.83 PPARG (0.48) PPARGPPARA
SCHEMBL50808 0.83 SRD5A2 (0.56) PPARGPPARA
SCHEMBL8332028 0.82 AKR1B1 (0.52) PPARGPPARA
SCHEMBL971331 0.80 SLC6A2 (0.47) SLC6A4SLC6A2SLC6A3KCNH2CACNA1C
SCHEMBL28489137 0.77 ALDH1A1 (0.51) PPARGPPARA
SCHEMBL3034916 0.77 SLC6A4 (0.55) SLC6A4SLC6A2SLC6A3KCNK2KCNH2
SCHEMBL4056401 0.77 SIGMAR1 (0.46) SLC6A4SLC6A2SLC6A3KCNH2CACNA1C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1060904-B1 A thermally sensitive recording medium JUJO PAPER CO LTD (JP) 2004-03-31 EP disclosed