SCHEMBL5080833

SCHEMBL5080833

CCOC(=O)CN(C)C(=O)CC

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.64
CA1 P00915 1/20 0.64
CA2 P00918 1/20 0.64
CA9 Q16790 1/20 0.64
GAA P10253 3/20 0.48
MGAM O43451 1/20 0.48
SI P14410 1/20 0.48
MGAM2 Q2M2H8 1/20 0.48
ALDH1A1 P00352 5/20 0.44
TRPA1 O75762 1/20 0.44
SOAT1 P35610 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
CYP1A2 P05177 1/20 0.39
LMNA P02545 1/20 0.39
HSD17B10 Q99714 1/20 0.39
KDM4E B2RXH2 2/20 0.37
POLB P06746 1/20 0.37
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1967964 0.85 CA12 (0.48) CA12CA1CA2CA9GAA
SCHEMBL10257097 0.84 CA12 (0.62) CA12CA1CA2CA9GAA
SCHEMBL1967853 0.83 CA12 (0.60) CA12CA1CA2CA9GAA
SCHEMBL25693305 0.83 CA12 (0.60) CA12CA1CA2CA9GAA
SCHEMBL2907468 0.83 CA12 (0.60) CA12CA1CA2CA9GAA
SCHEMBL24138916 0.83 CA12 (0.60) CA12CA1CA2CA9GAA
SCHEMBL8492079 0.83 CA12 (0.66) CA12CA1CA2CA9GAA
SCHEMBL2840377 0.83 CA12 (0.60) CA12CA1CA2CA9GAA
SCHEMBL7668945 0.82 CA12 (0.64) CA12CA1CA2CA9GAA
SCHEMBL2606996 0.81 CA12 (0.58) CA12CA1CA2CA9GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080125614-A1 Propylene polymer catalyst donor component INNOVENE USA (US) 2008-05-29 US claimed
EP-1866347-A2 PROPYLENE POLYMER CATALYST DONOR COMPONENT INEOS USA LLC (US) 2007-12-19 EP claimed
WO-2006110234-A2 PROPYLENE POLYMER CATALYST DONOR COMPONENT INEOS USA LLC (US) 2006-10-19 WO claimed
US-20230365556-A1 N-ACYL AMINO ACID COMPOUNDS AND METHODS OF USE PLIANT THERAPEUTICS, INC. (US) 2023-11-16 US disclosed
WO-2023151897-A1 TOFA ANALOGUES, SEBUM REDUCTION PREPARATIONS CONTAINING SAID TYPE OF ANALOGUES AND THE COSMETIC AND/OR THERAPEUTIC USE OF SAID TYPE OF ANALOGUES AS AN EFFECTIVE PRINCIPLE FOR REDUCING OR PREVENTING SEBUM BEIERSDORF AG (DE) 2023-08-17 WO disclosed
US-11673887-B2 N-acyl amino acid compounds and methods of use PLIANT THERAPEUTICS, INC. (US) 2023-06-13 US disclosed
EP-1866347-B1 PROPYLENE POLYMER CATALYST DONOR COMPONENT INEOS TECH USA LLC (US) 2018-05-09 EP disclosed
EP-1866347-B1 PROPYLENE POLYMER CATALYST DONOR COMPONENT INEOS TECH USA LLC (US) 2018-05-09 EP disclosed
US-8288606-B2 Magnesium, titanium, and halogen; internal electron donor, ethyl N-Boc-sarcosine, ethyl N-propionyl sarcosine, ethyl N-Boc-pipercolinate, N-carbobenzyloxy-L-proline methyl ester; polymerize propylene and ethylene or alpha-olefin; internal modifier which does not contain a phthalate derivative INEOS USA LLC (US) 2012-10-16 US disclosed
US-8288606-B2 Magnesium, titanium, and halogen; internal electron donor, ethyl N-Boc-sarcosine, ethyl N-propionyl sarcosine, ethyl N-Boc-pipercolinate, N-carbobenzyloxy-L-proline methyl ester; polymerize propylene and ethylene or alpha-olefin; internal modifier which does not contain a phthalate derivative INEOS USA LLC (US) 2012-10-16 US disclosed
US-8288606-B2 Magnesium, titanium, and halogen; internal electron donor, ethyl N-Boc-sarcosine, ethyl N-propionyl sarcosine, ethyl N-Boc-pipercolinate, N-carbobenzyloxy-L-proline methyl ester; polymerize propylene and ethylene or alpha-olefin; internal modifier which does not contain a phthalate derivative INEOS USA LLC (US) 2012-10-16 US disclosed
US-20080167308-A1 DIARYLAMINE-CONTAINING COMPOUNDS AND COMPOSITIONS, AND THEIR USE AS MODULATORS OF C-KIT RECEPTORS IRM LLC, A DELAWARE LIMITED LIABILITY COMAPNY (BM) 2008-07-10 US disclosed
US-20080139559-A1 DIARYLAMINE-CONTAINING COMPOUNDS AND COMPOSITIONS, AND THEIR USE AS MODULATORS OF C-KIT RECEPTORS IRM LLC, A DELAWARE LIMITED LIABILITY COMAPNY (BM) 2008-06-12 US disclosed
US-20080139597-A1 DIARYLAMINE-CONTAINING COMPOUNDS AND COMPOSITIONS, AND THEIR USE AS MODULATORS OF C-KIT RECEPTORS IRM LLC, A DELAWARE LIMITED LIABILITY COMAPNY (BM) 2008-06-12 US disclosed
US-20080125614-A1 Propylene polymer catalyst donor component INNOVENE USA (US) 2008-05-29 US disclosed
US-20080125614-A1 Propylene polymer catalyst donor component INNOVENE USA (US) 2008-05-29 US disclosed
US-20080125614-A1 Propylene polymer catalyst donor component INNOVENE USA (US) 2008-05-29 US disclosed
EP-1866347-A2 PROPYLENE POLYMER CATALYST DONOR COMPONENT INEOS USA LLC (US) 2007-12-19 EP disclosed
US-20070149538-A1 Diarylamine-Containing Compounds and Compositions, and their use as Modulators of C-Kit Receptors IRM LLC (BM) 2007-06-28 US disclosed
WO-2006110234-A2 PROPYLENE POLYMER CATALYST DONOR COMPONENT INEOS USA LLC (US) 2006-10-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080125614-A1 Propylene polymer catalyst donor component RAD52, PGR, DRD2 CA12 4077/4885CA1 4220/4885CA2 4423/4885
US-11673887-B2 N-acyl amino acid compounds and methods of use ITGA1, ITGB1, ITGAL CA12 2114/4885CA1 2164/4885CA2 1470/4885
US-20080139597-A1 DIARYLAMINE-CONTAINING COMPOUNDS AND COMPOSITIONS, AND THEIR USE AS MODULATORS OF C-KIT RECEPTORS KIT, PRKCH, PRKCE CA12 1969/4885CA1 2011/4885CA2 764/4885
US-20230365556-A1 N-ACYL AMINO ACID COMPOUNDS AND METHODS OF USE ITGA1, ITGB1, ITGAL CA12 2114/4885CA1 2164/4885CA2 1470/4885
US-20070149538-A1 Diarylamine-Containing Compounds and Compositions, and their use as Modulators of C-Kit Receptors KIT, PRKCH, PRKCE CA12 1969/4885CA1 2011/4885CA2 764/4885
US-20080167308-A1 DIARYLAMINE-CONTAINING COMPOUNDS AND COMPOSITIONS, AND THEIR USE AS MODULATORS OF C-KIT RECEPTORS KIT, PRKCH, PRKCE CA12 1969/4885CA1 2011/4885CA2 764/4885
US-20080139559-A1 DIARYLAMINE-CONTAINING COMPOUNDS AND COMPOSITIONS, AND THEIR USE AS MODULATORS OF C-KIT RECEPTORS KIT, PRKCH, PRKCE CA12 1969/4885CA1 2011/4885CA2 764/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.