SCHEMBL5080895

SCHEMBL5080895

Cc1cccc([SiH2]OCC(C)(C)CO[SiH2]c2cccc(C)c2C)c1C

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.36
ATM Q13315 1/20 0.36
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
RAB9A P51151 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
HTR1B P28222 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5077260 0.95 TRPA1 (0.33) TRPA1ATM
SCHEMBL5080795 0.91 TRPA1 (0.31) TRPA1ATM
SCHEMBL5080810 0.88
SCHEMBL3841318 0.79 TRPA1 (0.35) TRPA1ATMLMNAMAPTRAB9A
SCHEMBL28858184 0.78 TSHR (0.40) TRPA1ATMMAPT
SCHEMBL5080897 0.78 POLB (0.34) TRPA1ATMLMNAMAPTL3MBTL1
SCHEMBL11278838 0.76 HTR1B (0.35) TRPA1ATMLMNAMAPTHTR1B
SCHEMBL705275 0.76 TRPA1 (0.40) TRPA1ATMMAPTHTR1B
SCHEMBL5077247 0.75 POLB (0.32) MAPTL3MBTL1
SCHEMBL5409861 0.74 TRPA1 (0.41) TRPA1ATMMAPTHTR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US claimed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US claimed
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US disclosed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US disclosed