SCHEMBL5080897

SCHEMBL5080897

Cc1cccc([SiH2]OCC(CO[SiH2]c2cccc(C)c2C)(Cc2ccccc2)Cc2ccccc2)c1C

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.34
MAPT P10636 1/20 0.33
MAPK1 P28482 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
SLC6A2 P23975 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
CRHBP P24387 1/20 0.32
NPBWR1 P48145 1/20 0.32
CRHR2 Q13324 1/20 0.32
MCHR1 Q99705 1/20 0.32
LMNA P02545 1/20 0.31
CYP2D6 P10635 1/20 0.31
ALDH1A1 P00352 3/20 0.31
KMT2A Q03164 2/20 0.31
MEN1 O00255 1/20 0.31
TRPA1 O75762 1/20 0.31
ATM Q13315 1/20 0.31
SCN4A P35499 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5077247 0.96 POLB (0.32) POLBMAPTMAPK1TDP1L3MBTL1
SCHEMBL5081655 0.92 ALDH1A1 (0.30) POLBALDH1A1
SCHEMBL5080986 0.90 KMT2A (0.31) KMT2A
SCHEMBL5080895 0.78 TRPA1 (0.36) MAPTL3MBTL1LMNATRPA1ATM
SCHEMBL5077260 0.74 TRPA1 (0.33) TRPA1ATM
SCHEMBL3841318 0.72 TRPA1 (0.35) MAPTMAPK1L3MBTL1SMN1; SMN2LMNA
SCHEMBL19025038 0.71 CA4 (0.38) POLBMAPTMAPK1TDP1SMN1; SMN2
SCHEMBL5080795 0.71 TRPA1 (0.31) TRPA1ATM
SCHEMBL28858184 0.71 TSHR (0.40) POLBMAPTMAPK1TDP1SMN1; SMN2
SCHEMBL813617 0.69 SLC6A2 (0.46) SLC6A2TAAR1SMN1; SMN2LMNACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US claimed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US claimed
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US disclosed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US disclosed