SCHEMBL5080967

SCHEMBL5080967

CC(C)(C)[Si](C)(C)OCC(CO[Si](C)(C)C(C)(C)C)(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42
LMNA P02545 1/20 0.40
CYP2D6 P10635 1/20 0.40
TRPA1 O75762 1/20 0.36
MMP8 P22894 2/20 0.33
CYP2C9 P11712 2/20 0.33
CYP2C19 P33261 2/20 0.33
CYP1A2 P05177 1/20 0.33
PPARG P37231 1/20 0.33
PPARA Q07869 1/20 0.33
IDO1 P14902 1/20 0.32
BTN3A1 O00481 1/20 0.32
NPY5R Q15761 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP3A4 P08684 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HIF1A Q16665 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5077386 0.94 SLC6A2 (0.38) SLC6A2TAAR1LMNACYP2D6TRPA1
SCHEMBL5080932 0.91 SLC6A2 (0.36) SLC6A2TAAR1LMNACYP2D6TRPA1
SCHEMBL5075096 0.88 SLC6A2 (0.34) SLC6A2TAAR1LMNACYP2D6MMP8
SCHEMBL5081776 0.83 SLC6A2 (0.42) SLC6A2TAAR1LMNACYP2D6TRPA1
SCHEMBL5081767 0.79 TAAR1 (0.38) SLC6A2TAAR1LMNACYP2D6TRPA1
SCHEMBL5085326 0.79 SLC6A2 (0.38) SLC6A2TAAR1LMNACYP2D6TRPA1
SCHEMBL5080896 0.79 SLC6A2 (0.38) SLC6A2TAAR1LMNACYP2D6TRPA1
SCHEMBL5077173 0.77 SLC6A2 (0.37) SLC6A2TAAR1LMNACYP2D6TRPA1
SCHEMBL1315036 0.77 IDO1 (0.46) SLC6A2TAAR1LMNACYP2D6IDO1
SCHEMBL5080881 0.76 SLC6A2 (0.39) SLC6A2TAAR1LMNACYP2D6TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US claimed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US claimed
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US disclosed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US disclosed