SCHEMBL5081767

SCHEMBL5081767

C[Si](C)(Cc1ccccc1)OCC(CO[Si](C)(C)Cc1ccccc1)(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.38
SLC6A2 P23975 1/20 0.38
LMNA P02545 1/20 0.36
CYP2D6 P10635 1/20 0.36
NR1H2 P55055 1/20 0.34
NR1H3 Q13133 1/20 0.34
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
TRPA1 O75762 1/20 0.33
TSHR P16473 2/20 0.32
ALDH1A1 P00352 1/20 0.32
NPY5R Q15761 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HIF1A Q16665 1/20 0.32
TP53 P04637 1/20 0.31
FDPS P14324 1/20 0.31
EED O75530 1/20 0.31
DCAF15 Q66K64 1/20 0.31
AOC3 Q16853 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5078348 0.94 SLC6A2 (0.34) TAAR1SLC6A2LMNACYP2D6NR1H2
SCHEMBL5077300 0.91 ALDH1A1 (0.33) TAAR1SLC6A2LMNACYP2D6NR1H2
SCHEMBL5078143 0.88 MAPT (0.31) TAAR1SLC6A2
SCHEMBL5085326 0.86 SLC6A2 (0.38) TAAR1SLC6A2LMNACYP2D6CYP1A2
SCHEMBL5081776 0.83 SLC6A2 (0.42) TAAR1SLC6A2LMNACYP2D6CYP1A2
SCHEMBL5081803 0.83 SLC6A2 (0.36) TAAR1SLC6A2LMNACYP2D6CYP1A2
SCHEMBL5081735 0.83 TAAR1 (0.36) TAAR1SLC6A2LMNACYP2D6ALDH1A1
SCHEMBL5085401 0.81 TAAR1 (0.36) TAAR1SLC6A2LMNACYP2D6NR1H2
SCHEMBL5081838 0.81 SIGMAR1 (0.33) TAAR1SLC6A2LMNANR1H2NR1H3
SCHEMBL5081510 0.80 SLC6A2 (0.34) TAAR1SLC6A2LMNACYP2D6CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US claimed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US claimed
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US disclosed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US disclosed