SCHEMBL5081007

SCHEMBL5081007

O=C(N1CCCC1)C12CC3(C(=O)N4CCCC4)CC(C(=O)N4CCCC4)(C1)CC(C(=O)N1CCCC1)(C2)C3

nearest known ligand 0.65

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.65
LMNA P02545 1/20 0.65
MEN1 O00255 3/20 0.63
KMT2A Q03164 3/20 0.63
HSD11B1 P28845 8/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
MAPK1 P28482 1/20 0.44
ALDH1A1 P00352 2/20 0.43
ATM Q13315 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5085265 0.91 SMN1; SMN2 (0.57) SMN1; SMN2LMNAMEN1KMT2AHSD11B1
SCHEMBL5080851 0.91 SMN1; SMN2 (0.57) SMN1; SMN2LMNAMEN1KMT2AHSD11B1
SCHEMBL5078687 0.91 SMN1; SMN2 (0.57) SMN1; SMN2LMNAMEN1KMT2AHSD11B1
SCHEMBL22171175 0.85 MEN1 (0.65) SMN1; SMN2LMNAMEN1KMT2AHSD11B1
SCHEMBL30937104 0.84 HSD11B1 (0.56) SMN1; SMN2LMNAMEN1KMT2AHSD11B1
SCHEMBL5085229 0.84 SMN1; SMN2 (0.78) SMN1; SMN2LMNAMEN1KMT2AHSD11B1
SCHEMBL5568823 0.80 SMN1; SMN2 (1.00) SMN1; SMN2LMNAMEN1KMT2AHSD11B1
SCHEMBL29860554 0.77 HSD11B1 (0.83) SMN1; SMN2LMNAMEN1KMT2AHSD11B1
SCHEMBL5081813 0.77 SMN1; SMN2 (0.68) SMN1; SMN2LMNAMEN1KMT2AHSD11B1
SCHEMBL5078675 0.77 SMN1; SMN2 (0.68) SMN1; SMN2LMNAMEN1KMT2AHSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1462471-B1 Dielectric films and materials therefor DAICEL CHEM (JP) 2008-07-30 EP disclosed
US-20070078256-A1 Prepolymers, prepolymer compositions, high-molecular-weight polymers with pore structure, and dielectric films DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-04-05 US disclosed
US-7186454-B2 Dielectric films and materials therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-03-06 US disclosed
US-20070032556-A1 Aromatic polyamine derivative DAICEL CHEMICAL INSUSTRIES, LTD. (JP) 2007-02-08 US disclosed
EP-1683822-A1 PREPOLYMER, PREPOLYMER COMPOSITION, HIGH MOLECULAR WEIGHT POLYMER HAVING STRUCTURE CONTAINING HOLE AND ELECTRICALLY INSULATING FILM Daicel Chemical Industries, Ltd. (JP) 2006-07-26 EP disclosed
EP-1681284-A1 AROMATIC POLYAMINE DERIVATIVE Daicel Chemical Industries, Ltd. (JP) 2006-07-19 EP disclosed
EP-1462471-A1 Dielectric films and materials thereof Daicel Chemical Industries, Ltd. (JP) 2004-09-29 EP disclosed
US-20040175858-A1 Dielectric films and materials therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2004-09-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070032556-A1 Aromatic polyamine derivative SRM, PRMT1, KDM8 SMN1; SMN2 3372/4885LMNA 3440/4885MEN1 1236/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.