Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.78 |
| ▸ | LMNA | P02545 | 1/20 | 0.78 |
| ▸ | MEN1 | O00255 | 2/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.75 |
| ▸ | HSD11B1 | P28845 | 10/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5081813 | 0.92 | SMN1; SMN2 (0.68) | SMN1; SMN2LMNAMEN1KMT2AHSD11B1 | |
| SCHEMBL5078675 | 0.92 | SMN1; SMN2 (0.68) | SMN1; SMN2LMNAMEN1KMT2AHSD11B1 | |
| SCHEMBL29860554 | 0.91 | HSD11B1 (0.83) | SMN1; SMN2LMNAMEN1KMT2AHSD11B1 | |
| SCHEMBL5568823 | 0.88 | SMN1; SMN2 (1.00) | SMN1; SMN2LMNAMEN1KMT2AHSD11B1 | |
| SCHEMBL5081007 | 0.84 | SMN1; SMN2 (0.65) | SMN1; SMN2LMNAMEN1KMT2AHSD11B1 | |
| SCHEMBL3456185 | 0.83 | HSD11B1 (1.00) | SMN1; SMN2LMNAMEN1KMT2AHSD11B1 | |
| SCHEMBL5563669 | 0.81 | SMN1; SMN2 (0.86) | SMN1; SMN2LMNAMEN1KMT2AHSD11B1 | |
| SCHEMBL3457055 | 0.81 | HSD11B1 (1.00) | SMN1; SMN2LMNAMEN1KMT2AHSD11B1 | |
| SCHEMBL3455057 | 0.81 | HSD11B1 (1.00) | SMN1; SMN2LMNAMEN1KMT2AHSD11B1 | |
| SCHEMBL29269516 | 0.79 | HSD11B1 (0.66) | SMN1; SMN2LMNAMEN1KMT2AHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1462471-B1 | Dielectric films and materials therefor | DAICEL CHEM (JP) | 2008-07-30 | — | — | EP | disclosed |
| US-20070078256-A1 | Prepolymers, prepolymer compositions, high-molecular-weight polymers with pore structure, and dielectric films | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2007-04-05 | — | — | US | disclosed |
| US-7186454-B2 | Dielectric films and materials therefor | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2007-03-06 | — | — | US | disclosed |
| US-7186454-B2 | Dielectric films and materials therefor | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2007-03-06 | — | — | US | disclosed |
| US-7186454-B2 | Dielectric films and materials therefor | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2007-03-06 | — | — | US | disclosed |
| US-20070032556-A1 | Aromatic polyamine derivative | DAICEL CHEMICAL INSUSTRIES, LTD. (JP) | 2007-02-08 | — | — | US | disclosed |
| US-20060264667-A1 | Adamantanetricarboxylic acid derivatives | NAGANO SHINYA | 2006-11-23 | — | — | US | disclosed |
| US-7102027-B2 | Adamantanetricarboxylic acid derivatives | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2006-09-05 | — | — | US | disclosed |
| EP-1681284-A1 | AROMATIC POLYAMINE DERIVATIVE | Daicel Chemical Industries, Ltd. (JP) | 2006-07-19 | — | — | EP | disclosed |
| US-20040242923-A1 | Adamantanetricarboxylic acid derivatives | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2004-12-02 | — | — | US | disclosed |
| EP-1462471-A1 | Dielectric films and materials thereof | Daicel Chemical Industries, Ltd. (JP) | 2004-09-29 | — | — | EP | disclosed |
| US-20040175858-A1 | Dielectric films and materials therefor | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2004-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242923-A1 | Adamantanetricarboxylic acid derivatives | HCAR1, CA1, ALDH7A1 | SMN1; SMN2 2424/4885LMNA 1974/4885MEN1 1203/4885 |
| US-20070032556-A1 | Aromatic polyamine derivative | SRM, PRMT1, KDM8 | SMN1; SMN2 3372/4885LMNA 3440/4885MEN1 1236/4885 |
| US-20060264667-A1 | Adamantanetricarboxylic acid derivatives | CA1, HCAR1, ALDH7A1 | SMN1; SMN2 2289/4885LMNA 1367/4885MEN1 1259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.