SCHEMBL5081260

SCHEMBL5081260

C=C(C)C(=O)N(CCCC[SiH](OC)OC)C(=O)C(=C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4540247 0.85
SCHEMBL6565518 0.83
SCHEMBL26660041 0.76
SCHEMBL4375375 0.76 ZDHHC20 (0.33)
SCHEMBL26660016 0.75 LMNA (0.31)
SCHEMBL26660049 0.75 LMNA (0.31)
SCHEMBL26660021 0.74 ALDH1A1 (0.30)
SCHEMBL1305972 0.73 CES1 (0.32)
SCHEMBL7076373 0.71 TSHR (0.34)
SCHEMBL26660006 0.71 ALDH1A1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1858982-B1 SILICONE EMULSION, METHOD OF PREPARING SAME, AND COSMETIC INGREDIENT DOW CORNING (US) 2008-08-27 EP disclosed
US-20080182833-A1 Silicone Emulsion, Method of Preparing Same, and Cosmetic Ingredient DOW CORNING CORPORATION 2008-07-31 US disclosed
EP-1858982-A1 SILICONE EMULSION, METHOD OF PREPARING SAME, AND COSMETIC INGREDIENT Dow Corning Corporation (US) 2007-11-28 EP disclosed
WO-2006102010-A1 SILICONE EMULSION, METHOD OF PREPARING SAME, AND COSMETIC INGREDIENT DOW CORNING CORPORATION (US) 2006-09-28 WO disclosed
US-20040147647-A1 Polyorganosiloxane micro-emulsion composition and raw material for cosmetics DOW CORNING TORAY SILICONE CO., LTD. (JP) 2004-07-29 US disclosed
EP-1406575-A2 POLYORGANOSILOXANE MICRO-EMULSION COMPOSITION AND RAW MATERIAL FOR COSMETICS Dow Corning Toray Silicone Co.,Ltd. Patent Department (JP) 2004-04-14 EP disclosed
WO-2002094213-A2 POLYORGANOSILOXANE MICRO-EMULSION COMPOSITION AND RAW MATERIAL FOR COSMETICS DOW CORNING TORAY SILICONE CO.,LTD. (JP) 2002-11-28 WO disclosed
EP-0433727-B1 Silica-core silicone-shell particles, emulsion containing the same dispersed therein, and process for producing the emulsion TOSHIBA SILICONE (JP) 1995-08-02 EP disclosed
EP-0433906-B1 Thermoplastic resin and process for producing the same TOSHIBA SILICONE (JP) 1995-07-26 EP disclosed
US-5218014-A Graft polymer formed by graft polymerization of vinyl monomer onto colloidal silica core silicone shell particles TOSHIBA SILICONE CO., LTD. (JP) 1993-06-08 US disclosed
US-5188899-A SILICA-CORE SILICONE-SHELL PARTICLES, EMULSION CONTAINING THE SAME DISPERSED THEREIN, AND PROCESS FOR PRODUCING THE EMULSION TOSHIBA SILICONE CO., LTD. (JP) 1993-02-23 US disclosed
EP-0433906-A2 Thermoplastic resin and process for producing the same TOSHIBA SILICONE CO., LTD. (JP) 1991-06-26 EP disclosed
EP-0433727-A1 Silica-core silicone-shell particles, emulsion containing the same dispersed therein, and process for producing the emulsion TOSHIBA SILICONE CO., LTD. (JP) 1991-06-26 EP disclosed