SCHEMBL5081284

SCHEMBL5081284

CC(CC(C)OC(=O)c1ccccc1Cl)OC(=O)c1ccccc1Cl

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.62
KMT2A Q03164 1/20 0.59
ADRB2 P07550 2/20 0.50
ADRB1 P08588 2/20 0.50
ADRB3 P13945 2/20 0.50
ALDH1A1 P00352 4/20 0.48
NPC1 O15118 3/20 0.48
RAB9A P51151 3/20 0.48
MAPT P10636 2/20 0.48
POLB P06746 2/20 0.48
CES2 O00748 1/20 0.47
CES1 P23141 1/20 0.47
GAA P10253 2/20 0.45
LMNA P02545 1/20 0.45
HTR1E P28566 1/20 0.45
S1PR3 Q99500 1/20 0.45
SCN1A P35498 1/20 0.43
SCN2A Q99250 1/20 0.43
SCN3A Q9NY46 1/20 0.43
TSHR P16473 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29136152 0.87 USP2 (0.59) USP2KMT2AADRB2ADRB1ADRB3
SCHEMBL344758 0.84 USP2 (0.55) USP2KMT2AADRB2ADRB1ADRB3
SCHEMBL7741930 0.82 TSHR (0.58) USP2KMT2AALDH1A1NPC1SCN1A
SCHEMBL29395041 0.82 TSHR (0.58) USP2KMT2AALDH1A1NPC1SCN1A
SCHEMBL28347325 0.82 ALDH1A1 (0.71) USP2KMT2AADRB2ADRB1ADRB3
SCHEMBL2408720 0.81 SMN1; SMN2 (0.59) USP2KMT2AADRB2ADRB1ADRB3
SCHEMBL14690195 0.81 SMN1; SMN2 (0.59) USP2KMT2AADRB2ADRB1ADRB3
SCHEMBL6062597 0.81 ADRB2 (0.55) USP2KMT2AADRB2ADRB1ADRB3
SCHEMBL6062178 0.81 ADRB2 (0.55) USP2KMT2AADRB2ADRB1ADRB3
SCHEMBL6062309 0.81 ADRB2 (0.55) USP2KMT2AADRB2ADRB1ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7332455-B2 Catalyst component and catalyst for olefin polymerization as well as use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-02-19 US disclosed
US-20050119427-A1 Catalyst component and catalyst for olefin polymerization as well as use thereof BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2005-06-02 US disclosed