SCHEMBL5081655

SCHEMBL5081655

CCOCC(CO[SiH2]c1cccc(C)c1C)(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.30

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
RECQL P46063 1/20 0.30
MMP8 P22894 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5080897 0.92 POLB (0.34) ALDH1A1POLB
SCHEMBL5080986 0.90 KMT2A (0.31)
SCHEMBL5077247 0.88 POLB (0.32) POLB
SCHEMBL5080795 0.79 TRPA1 (0.31)
SCHEMBL1791345 0.78 SLC6A2 (0.43) ALDH1A1RECQLMMP8POLB
SCHEMBL5077364 0.73 SLC6A2 (0.36) ALDH1A1RECQLMMP8
SCHEMBL3841318 0.73 TRPA1 (0.35) ALDH1A1
SCHEMBL5080808 0.72 SLC6A2 (0.35) ALDH1A1RECQLMMP8
SCHEMBL5080895 0.72 TRPA1 (0.36)
SCHEMBL5077302 0.71 SLC6A2 (0.34) ALDH1A1RECQLMMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US claimed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US claimed
US-7399812-B2 Silicon ether compounds and a method for the preparation thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-07-15 US disclosed
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US disclosed
US-20060183873-A1 Silicon ether compounds and a method for the preparation thereof BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2006-08-17 US disclosed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US disclosed