Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5088070 | 0.76 | ALDH1A1 (0.52) | KDM4EHPGDRAB9AHSD17B10ALDH1A1 | |
| SCHEMBL31732891 | 0.74 | MKNK1 (0.36) | HPGDRAB9ANPSR1 | |
| SCHEMBL11714754 | 0.73 | KDM4E (0.43) | KDM4EHPGDGAARAB9AHSD17B10 | |
| SCHEMBL5081771 | 0.71 | SMN1; SMN2 (0.41) | HPGDALDH1A1SMN1; SMN2HTT | |
| SCHEMBL26608266 | 0.70 | LMNA (0.48) | KDM4EHPGDGAARAB9AHSD17B10 | |
| SCHEMBL31336260 | 0.70 | LMNA (0.48) | KDM4EHPGDGAARAB9AHSD17B10 | |
| SCHEMBL11300565 | 0.70 | ALDH1A1 (0.40) | RAB9AHSD17B10ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL13815988 | 0.70 | KDM4E (0.64) | KDM4EGAAALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL24558232 | 0.69 | KDM4E (0.42) | KDM4EHPGDGAARAB9AHSD17B10 | |
| SCHEMBL3637105 | 0.69 | KDM4E (0.53) | KDM4EHPGDGAARAB9AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008116816-A1 | COMBINATION OF CB2 LIGAND AND PARACETAMOL | GLAXO GROUP LIMITED (GB) | 2008-10-02 | — | — | WO | disclosed |