Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.50 |
| ▸ | ACHE | P22303 | 6/20 | 0.50 |
| ▸ | BCHE | P06276 | 5/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9721323 | 0.98 | PTGS2 (0.49) | PTGS2ACHEBCHECHRM2HTR1A | |
| SCHEMBL6394314 | 0.90 | PTGS2 (0.57) | PTGS2ACHEBCHECHRM2CHRM1 | |
| SCHEMBL1372415 | 0.89 | ACHE (0.42) | PTGS2ACHEBCHECHRM2HTR1A | |
| Tetrahydrofuran SCHEMBL28729713 | 0.85 | PTGS2 (0.46) | PTGS2ACHEBCHECHRM2HTR1A | |
| SCHEMBL8584928 | 0.84 | CHRM2 (0.51) | PTGS2ACHEBCHECHRM2HTR1A | |
| SCHEMBL10230188 | 0.82 | CHRM2 (0.39) | PTGS2ACHEBCHECHRM2HTR1A | |
| SCHEMBL10535136 | 0.81 | PTGS2 (0.50) | PTGS2ACHEBCHESLC6A2SLC6A4 | |
| SCHEMBL3906858 | 0.81 | ACHE (0.50) | PTGS2ACHEBCHENPC1RAB9A | |
| SCHEMBL6947245 | 0.80 | ACHE (0.46) | PTGS2ACHEBCHESLC6A2SLC6A4 | |
| SCHEMBL13314726 | 0.80 | GAA (0.44) | PTGS2ACHEBCHECHRM2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114409698-B | Triphenylphosphine derivative ligand with large steric hindrance, preparation method and application thereof | 东莞理工学院 | 2024-02-09 | — | — | CN | claimed |
| CN-117486935-A | Heterogeneous catalyst, preparation method and method for catalyzing carbon dioxide conversion by heterogeneous catalyst | 肯特催化材料股份有限公司 | 2024-02-02 | — | — | CN | claimed |
| CN-114409698-A | Triphenylphosphine derivative ligand with large steric hindrance, preparation method and application thereof | 东莞理工学院 | 2022-04-29 | — | — | CN | claimed |
| CN-103571459-B | Aldehyde group functionalized pyridyl benzoimidazole fluorescent material and preparation method thereof | UNIV TIANJIN | 2015-07-08 | — | — | CN | claimed |
| CN-103571459-A | Aldehyde group functionalized pyridyl benzoimidazole fluorescent material and preparation method thereof | UNIV TIANJIN | 2014-02-12 | — | — | CN | claimed |
| JP-6234690-A | — | — | None | — | — | JP | disclosed |
| EP-4727591-A1 | SMARCA2 DEGRADERS AND USES THEREOF | Astrazeneca AB (SE) | 2026-04-22 | — | — | EP | disclosed |
| US-12187712-B2 | Cardiac sarcomere inhibitors | CYTOKINETICS, INC. (US) | 2025-01-07 | — | — | US | disclosed |
| WO-2024256988-A1 | SMARCA2 DEGRADERS AND USES THEREOF | ASTRAZENECA AB (SE) | 2024-12-19 | — | — | WO | disclosed |
| US-20240208932-A1 | ARYLAMINO DERIVATIVE ESTROGEN RECEPTOR MODULATOR AND USE THEREOF | XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2024-06-27 | — | — | US | disclosed |
| US-20240186520-A1 | RESIN COMPOSITION FOR SECONDARY BATTERY ELECTRODE | SEKISUI CHEMICAL CO., LTD. (JP) | 2024-06-06 | — | — | US | disclosed |
| EP-3514140-B1 | FLUORINE-BASED COMPOUND, ORGANIC LIGHT-EMITTING DEVICE USING SAME AND METHOD FOR PREPARING SAME | LG CHEMICAL LTD (KR) | 2024-03-06 | — | — | EP | disclosed |
| EP-0411736-B1 | 11-Beta substituted 16-alpha, 17-alpha-methylene-estra-4,9-dien-3-one | SCHERING AG (DE) | 1994-05-04 | — | — | EP | disclosed |
| US-5162312-A | 11β-substituted 16α, 17α-methylene-estra-4,9-dien-3-ones | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-11-10 | — | — | US | disclosed |
| WO-1991001994-A1 | 11β-SUBSTITUTED 16α,17α-METHYLENE-ESTRA-4,9-DIENE-3-ONES | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1991-02-21 | — | — | WO | disclosed |
| EP-0411736-A1 | 11-Beta substituted 16-alpha, 17-alpha-methylene-estra-4,9-dien-3-one | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-02-06 | — | — | EP | disclosed |
| EP-0153678-A1 | Cinnamic acid derivatives, processes for the preparation thereof and pharmaceutical compositions | Tanabe Seiyaku Co., Ltd. (JP) | 1985-09-04 | — | — | EP | disclosed |
| US-4427682-A | ANTICOAGULANTS, ANTIINFLAMMATORY, HYPOTENSIVE, OR ANTIALLERGEN AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1984-01-24 | — | — | US | disclosed |
| US-4317828-A | ANTIINFLAMMATORY AGENTS, HYPOTENSIVE AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-03-02 | — | — | US | disclosed |
| US-4271170-A | THROMBOXANE SYNTHETASE ENZYME INHIBITOR USEFUL IN TREATING INFLAMMATION, HYPERTENSION, THROMBUS, CEREBRAL APOPLEXY, ASTHMA, AND CARDIOVASCULAR DISORDERS | ONO PHARMACEUTICAL CO., LTD., (JP) | 1981-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240208932-A1 | ARYLAMINO DERIVATIVE ESTROGEN RECEPTOR MODULATOR AND USE THEREOF | GPER1, ESR1, ESRRA | PTGS2 1491/4885ACHE 4547/4885BCHE 3888/4885 |
| US-12187712-B2 | Cardiac sarcomere inhibitors | TNNI3, TNNT2, MYLK2 | PTGS2 2968/4885ACHE 2835/4885BCHE 4787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.