Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 1/20 | 0.58 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.52 |
| ▸ | FDPS | P14324 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | AGER | Q15109 | 4/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7404412 | 0.78 | ALDH1A1 (0.65) | MAPTLMNAKDM4EKMT2ATDP1 | |
| SCHEMBL9080800 | 0.77 | EGLN3 (0.51) | APAF1FDPSLMNAEGLN3KDM4E | |
| SCHEMBL4064250 | 0.76 | EGLN3 (0.65) | APAF1MAPTLMNAEGLN3KDM4E | |
| SCHEMBL4064248 | 0.74 | APAF1 (0.70) | APAF1GGPS1FDPSMAPTPOLB | |
| SCHEMBL27803082 | 0.74 | CYP1A2 (0.51) | APAF1MAPTPOLBKDM4ECYP3A4 | |
| SCHEMBL5884818 | 0.74 | TDP1 (0.61) | MAPTLMNAEGLN3KDM4EKMT2A | |
| SCHEMBL5323231 | 0.73 | APAF1 (0.69) | APAF1GGPS1FDPSMAPTPOLB | |
| SCHEMBL22660983 | 0.73 | APAF1 (0.69) | APAF1GGPS1FDPSMAPTPOLB | |
| SCHEMBL2446284 | 0.73 | APAF1 (1.00) | APAF1GGPS1FDPSMAPTPOLB | |
| SCHEMBL13587954 | 0.73 | MAPT (0.66) | APAF1GGPS1FDPSMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1883419-A2 | GLUCAGON-LIKE PEPTIDE 1 (GLP-1) RECEPTOR AGONISTS AND THEIR PHARMACOLOGICAL METHODS OF USE | Bayer Pharmaceuticals Corporation (US) | 2008-02-06 | — | — | EP | disclosed |
| WO-2006121860-A2 | GLUCAGON-LIKE PEPTIDE 1 (GLP-1) RECEPTOR AGONISTS AND THEIR PHARMACOLOGICAL METHODS OF USE | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-11-16 | — | — | WO | disclosed |