Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.51 |
| ▸ | APAF1 | O14727 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.47 |
| ▸ | FDPS | P14324 | 1/20 | 0.47 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.46 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823327 | 0.93 | EGLN3 (0.58) | EGLN3APAF1TDP1KDM4ENPC1 | |
| SCHEMBL28108555 | 0.84 | EGLN3 (0.52) | EGLN3APAF1TDP1KDM4ENPC1 | |
| SCHEMBL28235209 | 0.84 | EGLN3 (0.55) | EGLN3APAF1TDP1KDM4ENPC1 | |
| SCHEMBL7404412 | 0.81 | ALDH1A1 (0.65) | TDP1KDM4ENPC1ALDH1A1MEN1 | |
| SCHEMBL5613880 | 0.81 | KDM4E (0.56) | EGLN3APAF1TDP1KDM4ENPC1 | |
| SCHEMBL4064250 | 0.79 | EGLN3 (0.65) | EGLN3APAF1TDP1KDM4EALDH1A1 | |
| SCHEMBL9670554 | 0.79 | TDP1 (0.59) | APAF1TDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL5884818 | 0.77 | TDP1 (0.61) | EGLN3TDP1KDM4EALDH1A1MEN1 | |
| SCHEMBL5082052 | 0.77 | APAF1 (0.58) | EGLN3APAF1TDP1KDM4ENPC1 | |
| SCHEMBL29145104 | 0.76 | ALDH1A1 (0.55) | KDM4ENPC1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995032957-A1 | NOVEL ETHOXYCARBONYLOXYMETHYL DERIVATIVES OF SUBSTITUTED BENZIMIDAZOLES | ASTRA AKTIEBOLAG (SE) | 1995-12-07 | — | — | WO | claimed |
| WO-1991009029-A1 | THERAPEUTICALLY ACTIVE CHLORO SUBSTITUTED BENZIMIDAZOLES, PROCESSES FOR THEIR PREPARATION AS WELL AS THEIR USE | Aktiebolaget Hässle (SE) | 1991-06-27 | — | — | WO | claimed |
| WO-1996016959-A1 | A PROCESS FOR THE PREPARATION OF BENZIMIDAZOLE DERIVATIVES | ASTRA AKTIEBOLAG (SE) | 1996-06-06 | — | — | WO | disclosed |