Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ING2 | Q9H160 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11856695 | 0.98 | ALDH1A1 (0.46) | ALDH1A1KDM4EGAAPTGS2PTGS1 | |
| SCHEMBL11344310 | 0.85 | NT5E (0.41) | ALDH1A1KDM4EGAAPTGS2PTGS1 | |
| SCHEMBL14120915 | 0.79 | PTGS2 (0.44) | ALDH1A1KDM4EGAAPTGS2PTGS1 | |
| SCHEMBL24539858 | 0.77 | CXCR5 (0.36) | ALDH1A1LCKFYNING2 | |
| SCHEMBL13966789 | 0.77 | ABCB11 (0.39) | ALDH1A1KDM4EGAALCKFYN | |
| SCHEMBL5082244 | 0.76 | PTGS2 (0.45) | ALDH1A1KDM4EGAAPTGS2PTGS1 | |
| SCHEMBL10498837 | 0.76 | ALDH1A1 (0.52) | ALDH1A1PTGS2PTGS1HPGDLMNA | |
| SCHEMBL2217165 | 0.75 | CYP3A4 (0.52) | ALDH1A1KDM4EGAAPTGS2HPGD | |
| SCHEMBL11802845 | 0.75 | TDP1 (0.54) | ALDH1A1KDM4ETPMTHPGDLCK | |
| SCHEMBL16308957 | 0.75 | ALDH1A1 (0.42) | ALDH1A1GAALCKFYNLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497374-B1 | FILLER REINFORCED POLYETHER IMIDE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF | GEN ELECTRIC (US) | 2008-08-13 | — | — | EP | disclosed |
| US-7244778-B2 | Filler reinforced polyether imide resin composition and molded article thereof | GENERAL ELECTRIC COMPANY (US) | 2007-07-17 | — | — | US | disclosed |
| US-20050131105-A1 | Filler reinforced polyether imide resin composition and molded article thereof | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2005-06-16 | — | — | US | disclosed |
| EP-1497374-A1 | FILLER REINFORCED POLYETHER IMIDE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF | GENERAL ELECTRIC COMPANY (US) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003087226-A1 | FILLER REINFORCED POLYETHER IMIDE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF | GENERAL ELECTRIC COMPAMY (US) | 2003-10-23 | — | — | WO | disclosed |