Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.40 |
| ▸ | HTR2B | P41595 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5082332 | 1.00 | HTR1A (0.40) | HTR1AHTR2BDRD2HRH3 | |
| Hydrochloric Acid SCHEMBL1253093 | 0.99 | HTR1A (0.39) | HTR1AHTR2BDRD2HRH3 | |
| Hydrochloric Acid SCHEMBL1253096 | 0.99 | HTR1A (0.39) | HTR1AHTR2BDRD2HRH3 | |
| SCHEMBL5082745 | 0.83 | FAAH (0.39) | — | |
| SCHEMBL5082771 | 0.83 | FAAH (0.39) | — | |
| Hydrochloric Acid SCHEMBL1254161 | 0.82 | FAAH (0.39) | — | |
| Hydrochloric Acid SCHEMBL1254167 | 0.82 | FAAH (0.39) | — | |
| SCHEMBL5076267 | 0.80 | KIT (0.41) | — | |
| Hydrochloric Acid SCHEMBL1251761 | 0.79 | KIT (0.40) | — | |
| Hydrochloric Acid SCHEMBL1251765 | 0.79 | KIT (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1608377-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING INHIBITORS OF FAB I AND FURTHER ANTIBIOTICS | AFFINIUM PHARM INC (CA) | 2008-10-01 | — | — | EP | claimed |