Toluic Acid

Toluic Acid

SCHEMBL5082804

CC(O)C(C)O.Cc1ccccc1C(=O)O.Cc1ccccc1C(=O)O

nearest known ligand 0.79

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.53
HPGD P15428 4/20 0.53
KDM4E B2RXH2 4/20 0.53
HSD17B10 Q99714 2/20 0.53
MYC P01106 1/20 0.53
ALOX15 P16050 1/20 0.52
ERCC5 P28715 1/20 0.52
FEN1 P39748 1/20 0.52
CYP3A4 P08684 2/20 0.50
CYP2C9 P11712 2/20 0.50
KMT2A Q03164 2/20 0.50
POLB P06746 2/20 0.49
MAPT P10636 1/20 0.48
HDAC8 Q9BY41 1/20 0.48
NAPRT Q6XQN6 2/20 0.47
AKR1C3 P42330 2/20 0.47
MEN1 O00255 1/20 0.47
AKR1B10 O60218 1/20 0.47
TRPA1 O75762 1/20 0.47
ABCB11 O95342 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluic Acid SCHEMBL28123045 0.91 ALDH1A1 (0.62) ALDH1A1HPGDKDM4EHSD17B10MYC
Toluic Acid SCHEMBL148201 0.89 ALDH1A1 (0.65) ALDH1A1HPGDKDM4EHSD17B10MYC
Toluic Acid SCHEMBL28037745 0.89 ALDH1A1 (0.65) ALDH1A1HPGDKDM4EHSD17B10MYC
Toluic Acid SCHEMBL4152 0.89 ALDH1A1 (0.65) ALDH1A1HPGDKDM4EHSD17B10MYC
Toluic Acid SCHEMBL29414127 0.89 ALDH1A1 (0.65) ALDH1A1HPGDKDM4EHSD17B10MYC
Toluic Acid SCHEMBL6571818 0.89 ALDH1A1 (0.65) ALDH1A1HPGDKDM4EHSD17B10MYC
Toluic Acid SCHEMBL4730975 0.87 ALDH1A1 (0.62) ALDH1A1HPGDKDM4EHSD17B10MYC
Toluic Acid SCHEMBL6913659 0.87 ALDH1A1 (0.62) ALDH1A1HPGDKDM4EHSD17B10MYC
Toluic Acid SCHEMBL6913552 0.87 ALDH1A1 (0.62) ALDH1A1HPGDKDM4EHSD17B10MYC
Toluic Acid SCHEMBL5748070 0.87 ALDH1A1 (0.62) ALDH1A1HPGDKDM4EHSD17B10MYC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1666505-B1 CATALYST COMPONENTS CATALYSTS FOR OLEFINIC POLYMERIZATION AND THE USE THEREOF CHINA PETROLEUM & CHEMICAL (CN) 2016-03-23 EP disclosed
US-7332455-B2 Catalyst component and catalyst for olefin polymerization as well as use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-02-19 US disclosed
EP-1666505-A1 CATALYST COMPONENTS CATALYSTS FOR OLEFINIC POLYMERIZATION AND THE USE THEREOF China Petroleum & Chemical Corporation (CN) 2006-06-07 EP disclosed
US-20050119427-A1 Catalyst component and catalyst for olefin polymerization as well as use thereof BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2005-06-02 US disclosed