SCHEMBL5082856

SCHEMBL5082856

C=C(OC(=O)c1ccc(OC)cc1)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.61
CES1 P23141 2/20 0.61
MAPT P10636 5/20 0.55
NPC1 O15118 5/20 0.55
RAB9A P51151 5/20 0.55
CDK5 Q00535 2/20 0.55
CDK5R1 Q15078 2/20 0.55
PKM P14618 1/20 0.55
CA1 P00915 2/20 0.55
CA2 P00918 2/20 0.55
KMT2A Q03164 2/20 0.52
POLB P06746 1/20 0.52
MEN1 O00255 1/20 0.52
PAX8 Q06710 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
ALDH1A1 P00352 2/20 0.49
MAPK1 P28482 1/20 0.49
TSHR P16473 1/20 0.48
KCNK9 Q9NPC2 1/20 0.48
KDM4E B2RXH2 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4196144 0.93 CA1 (0.62) CES2CES1MAPTRAB9ACA1
SCHEMBL247020 0.88 CES2 (0.71) CES2CES1MAPTNPC1RAB9A
SCHEMBL382312 0.86 LMNA (0.56) CES2CES1MAPTKMT2APOLB
SCHEMBL14099145 0.83 CES2 (0.55) CES2CES1MAPTNPC1RAB9A
SCHEMBL5079219 0.83 MAPT (0.60) CES2CES1MAPTNPC1RAB9A
SCHEMBL5082794 0.83 MAPT (0.60) CES2CES1MAPTNPC1RAB9A
Methyl 4-Methoxybenzoate SCHEMBL28249391 0.80 CA1 (0.84) CES2CES1MAPTNPC1RAB9A
SCHEMBL7649401 0.80 CES2 (0.71) CES2CES1MAPTNPC1RAB9A
SCHEMBL11271050 0.80 CES2 (0.71) CES2CES1MAPTNPC1RAB9A
SCHEMBL756485 0.80 NR1I2 (0.56) CES2CES1MAPTCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1868984-B1 BENZOIC ACID ESTER COMPOUNDS, COMPOSITIONS, USES AND METHODS RELATED THERETO FERRER INT (ES) 2017-07-19 EP claimed
US-8545816-B2 1-(4-methoxyphenyl)-vinyl 4-tert-butylbenzoate; cosmetic, pharmaceutical, personal care and industrial preparations as sunscreens; ultraviolet radiation protection FERRER INTERNACIONAL, S.A. (ES) 2013-10-01 US claimed
US-20080206158-A1 Benzoic Acid Ester Compounds, Compositions, Uses and Methods Related Thereto FERRER INTERNACIONAL, S.A. (ES) 2008-08-28 US claimed
CN-101180264-A Benzoic acid ester compounds, compositions, uses and methods related thereto FERRER INT (ES) 2008-05-14 CN claimed
EP-1868984-A2 BENZOIC ACID ESTER COMPOUNDS, COMPOSITIONS, USES AND METHODS RELATED THERETO FERRER INTERNACIONAL, S.A. (ES) 2007-12-26 EP claimed
EP-1707558-A1 Benzoic acid ester compounds, compositions, uses and methods related thereto FERRER INTERNACIONAL, S.A. (ES) 2006-10-04 EP claimed
WO-2006100225-A2 BENZOIC ACID ESTER COMPOUNDS, COMPOSITIONS, USES AND METHODS RELATED THERETO FERRER INTERNACIONAL, S. A. (ES) 2006-09-28 WO claimed
US-20260028302-A1 PROCESS FOR PREPARING BENZOIC ACID ESTERS AND INTERMEDIATES THEREOF ROKA FURADADA S L (ES) 2026-01-29 US disclosed
US-20250360066-A1 COMPOSITION COMPRISING A PHOTOCHEMICAL ULTRAVIOLET ABSORBER PRECURSOR AND A COMPOUND FOR INCREASING THEIR PHOTOCHEMICAL CONVERSION RATE ROKA FURADADA S L (ES) 2025-11-27 US disclosed
EP-4561523-A1 COMPOSITION COMPRISING A PHOTOCHEMICAL ULTRAVIOLET ABSORBER PRECURSOR AND A COMPOUND FOR INCREASING THEIR PHOTOCHEMICAL CONVERSION RATE Roka Furadada, SL (ES) 2025-06-04 EP disclosed
CN-119677713-A Processes for preparing benzoates and intermediates thereof 罗卡福拉达有限公司 2025-03-21 CN disclosed
WO-2024013382-A9 PROCESS FOR PREPARING BENZOIC ACID ESTERS AND INTERMEDIATES THEREOF ROKA FURADADA, S.L. (ES) 2024-04-18 WO disclosed
WO-2024023286-A1 COMPOSITION COMPRISING A PHOTOCHEMICAL ULTRAVIOLET ABSORBER PRECURSOR AND A COMPOUND FOR INCREASING THEIR PHOTOCHEMICAL CONVERSION RATE ROKA FURADADA, S.L. (ES) 2024-02-01 WO disclosed
US-8545816-B2 1-(4-methoxyphenyl)-vinyl 4-tert-butylbenzoate; cosmetic, pharmaceutical, personal care and industrial preparations as sunscreens; ultraviolet radiation protection FERRER INTERNACIONAL, S.A. (ES) 2013-10-01 US disclosed
CN-101180264-B Benzoic acid ester compounds, compositions, uses and methods related thereto FERRER INT 2013-03-27 CN disclosed
US-20080206158-A1 Benzoic Acid Ester Compounds, Compositions, Uses and Methods Related Thereto FERRER INTERNACIONAL, S.A. (ES) 2008-08-28 US disclosed
CN-101180264-A Benzoic acid ester compounds, compositions, uses and methods related thereto FERRER INT (ES) 2008-05-14 CN disclosed
EP-1868984-A2 BENZOIC ACID ESTER COMPOUNDS, COMPOSITIONS, USES AND METHODS RELATED THERETO FERRER INTERNACIONAL, S.A. (ES) 2007-12-26 EP disclosed
EP-1707558-A1 Benzoic acid ester compounds, compositions, uses and methods related thereto FERRER INTERNACIONAL, S.A. (ES) 2006-10-04 EP disclosed
WO-2006100225-A2 BENZOIC ACID ESTER COMPOUNDS, COMPOSITIONS, USES AND METHODS RELATED THERETO FERRER INTERNACIONAL, S. A. (ES) 2006-09-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250360066-A1 COMPOSITION COMPRISING A PHOTOCHEMICAL ULTRAVIOLET ABSORBER PRECURSOR AND A COMPOUND FOR INCREASING THEIR PHOTOCHEMICAL CONVERSION RATE TYR, PAH, ERCC4 CES2 2738/4885CES1 1539/4885MAPT 387/4885
US-20080206158-A1 Benzoic Acid Ester Compounds, Compositions, Uses and Methods Related Thereto VKORC1, CYP51A1, CYP19A1 CES2 789/4885CES1 116/4885MAPT 2950/4885
US-20260028302-A1 PROCESS FOR PREPARING BENZOIC ACID ESTERS AND INTERMEDIATES THEREOF DHCR24, BCKDK, CYP2B6 CES2 246/4885CES1 110/4885MAPT 4867/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.