Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | C1R | P00736 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24158011 | 0.84 | NPC1 (0.59) | NPC1RAB9AALDH1A1MAPTMAPK1 | |
| SCHEMBL183017 | 0.83 | HTT (0.59) | NPC1RAB9AHPGDALDH1A1MAPT | |
| SCHEMBL5085672 | 0.83 | RAB9A (0.56) | NPC1RAB9AHPGDALDH1A1MAPT | |
| SCHEMBL29511793 | 0.83 | HTT (0.59) | NPC1RAB9AHPGDALDH1A1MAPT | |
| Bicarbonate SCHEMBL31082205 | 0.82 | RAB9A (0.61) | NPC1RAB9AHPGDALDH1A1ALOX12 | |
| SCHEMBL1713041 | 0.81 | HTT (0.56) | NPC1RAB9AHPGDALDH1A1MAPT | |
| Water SCHEMBL8601906 | 0.81 | HTT (0.56) | NPC1RAB9AHPGDALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL3212348 | 0.81 | HTT (0.56) | NPC1RAB9AHPGDALDH1A1MAPT | |
| Oxalic Acid SCHEMBL31082365 | 0.80 | RAB9A (0.59) | NPC1RAB9AHPGDALDH1A1ALOX12 | |
| SCHEMBL30671657 | 0.79 | ALDH1A1 (0.50) | NPC1RAB9AHPGDALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375242-B2 | Catalysts for olefin polymerization | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-05-20 | — | — | US | disclosed |
| US-20030027957-A1 | Catalysts for olefin polymerization | HICKS FREDERICK (US) | 2003-02-06 | — | — | US | disclosed |
| US-6451940-B1 | THE USE OF AMINOTROPONES AS LIGANDS FOR NICKEL CONTAINING OLEFIN POLYMERIZATION CATALYSTS | E. I. DU PONT DE NEMOURS AND COMPANY | 2002-09-17 | — | — | US | disclosed |
| EP-1237951-A1 | CATALYSTS FOR OLEFIN POLYMERIZATIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001030865-A1 | CATALYSTS FOR OLEFIN POLYMERIZATIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2001-05-03 | — | — | WO | disclosed |