Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.47 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.42 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5082965 | 0.85 | RIPK1 (0.46) | RAB9ANPC1PTGS2HSD17B10MAPT | |
| SCHEMBL5088738 | 0.84 | RIPK1 (0.47) | RAB9ANPC1PTGS2HSD17B10MAPT | |
| SCHEMBL5083060 | 0.83 | NPC1 (0.60) | RAB9ANPC1PTGS2HSD17B10MAPT | |
| SCHEMBL1921293 | 0.83 | RAPGEF4 (0.57) | RAB9ANPC1PTGS2MAPTRAPGEF4 | |
| SCHEMBL4800221 | 0.81 | RAPGEF4 (0.55) | RAB9ANPC1PTGS2MAPTMAPK1 | |
| SCHEMBL7643916 | 0.80 | PTGS2 (0.52) | RAB9ANPC1PTGS2HSD17B10ALOX12 | |
| SCHEMBL5086126 | 0.76 | CXCL8 (0.56) | RAB9ANPC1PTGS2HSD17B10MAPT | |
| SCHEMBL5082967 | 0.76 | NPC1 (0.52) | RAB9ANPC1HSD17B10MAPTALOX12 | |
| SCHEMBL7851667 | 0.76 | PTGS2 (0.73) | PTGS2HSD17B10MAPTMAPK1POLB | |
| SCHEMBL1821014 | 0.76 | LMNA (0.51) | RAB9ANPC1HSD17B10MAPTALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375242-B2 | Catalysts for olefin polymerization | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-05-20 | — | — | US | disclosed |
| US-20030027957-A1 | Catalysts for olefin polymerization | HICKS FREDERICK (US) | 2003-02-06 | — | — | US | disclosed |
| US-6451940-B1 | THE USE OF AMINOTROPONES AS LIGANDS FOR NICKEL CONTAINING OLEFIN POLYMERIZATION CATALYSTS | E. I. DU PONT DE NEMOURS AND COMPANY | 2002-09-17 | — | — | US | disclosed |