SCHEMBL5083160

SCHEMBL5083160

CCOc1ccc(O)c(C(C)(C)C)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.56
HSD17B10 Q99714 2/20 0.52
ALOX15 P16050 2/20 0.52
NR1I2 O75469 1/20 0.52
LMNA P02545 1/20 0.52
CYP2C9 P11712 1/20 0.52
MIF P14174 1/20 0.52
TYR P14679 1/20 0.52
HTT P42858 1/20 0.52
NFE2L2 Q16236 1/20 0.52
ESRRA P11474 3/20 0.51
GAA P10253 2/20 0.50
ATM Q13315 2/20 0.50
XBP1 P17861 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
NR1H4 Q96RI1 4/20 0.48
NQO1 P15559 1/20 0.46
MAPT P10636 3/20 0.46
POLB P06746 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8632740 0.90 ESRRA (0.61) ALDH1A1HSD17B10ALOX15NR1I2LMNA
SCHEMBL2815926 0.86 GAA (0.58) ALDH1A1HSD17B10ALOX15NR1I2LMNA
SCHEMBL9150850 0.86 ALDH1A1 (0.53) ALDH1A1HSD17B10ALOX15NR1I2LMNA
SCHEMBL9408554 0.84 ALDH1A1 (0.78) ALDH1A1HSD17B10ALOX15NR1I2LMNA
SCHEMBL5953654 0.84 MAPT (0.45) ALDH1A1HSD17B10ALOX15LMNAGAA
SCHEMBL9150596 0.84 ALDH1A1 (0.45) ALDH1A1HSD17B10ALOX15GAAL3MBTL1
SCHEMBL11799605 0.83 ALDH1A1 (0.43) ALDH1A1HSD17B10ALOX15LMNAHTT
SCHEMBL7823292 0.82 ALDH1A1 (0.53) ALDH1A1HSD17B10ALOX15NR1I2LMNA
SCHEMBL5634319 0.82 NR5A1 (0.56) ALDH1A1HSD17B10ALOX15NR1I2LMNA
SCHEMBL11654654 0.82 NR5A1 (0.56) ALDH1A1HSD17B10ALOX15NR1I2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5399623-A Semiconductors with sealing rubbers DAIKIN INDUSTRIES, LTD. (JP) 1995-03-21 US claimed
US-12559458-B2 Co-crystals or salts of psilocin and methods of treatment therewith Reset Pharmaceuticals, Inc. (US) 2026-02-24 US disclosed
EP-4486448-A1 CO-CRYSTALS OR SALTS COMPRISING PSILOCIN Reset Pharmaceuticals, Inc. (US) 2025-01-08 EP disclosed
US-20240383849-A1 CO-CRYSTAL OR SALT Reset Pharmaceuticals, Inc. 2024-11-21 US disclosed
CN-118871423-A Co-crystals or salts comprising xylometacin 雷塞特制药股份有限公司 2024-10-29 CN disclosed
US-12060328-B2 Co-crystals or salts of psilocybin and methods of treatment therewith Reset Pharmaceuticals, Inc. (US) 2024-08-13 US disclosed
WO-2023168023-A1 CO-CRYSTALS OR SALTS COMPRISING PSILOCIN Reset Pharmaceuticals, Inc. (US) 2023-09-07 WO disclosed
WO-2023168022-A1 CO-CRYSTALS OR SALTS COMPRISING PSILOCYBIN Reset Pharmaceuticals, Inc. (US) 2023-09-07 WO disclosed
US-20230279032-A1 CO-CRYSTAL OR SALT Reset Pharmaceuticals, Inc. 2023-09-07 US disclosed
US-20230202978-A1 CO-CRYSTAL OR SALT Reset Pharmaceuticals, Inc. 2023-06-29 US disclosed
US-20080125531-A1 Polymerizable Composition, Thermoplastic Resin Composition, Crosslinked Resin, And Crosslinked Resin Composite Materials ZEON COROPRATION (JP) 2008-05-29 US disclosed
EP-1589054-A1 POLYMERIZABLE COMPOSITION, THERMOPLASTIC RESIN COMPOSITION, CROSSLINKED RESIN, AND CROSSLINKED RESIN COMPOSITE MATERIALS Zeon Corporation (JP) 2005-10-26 EP disclosed
US-5849732-A Phenol compound having antioxidative activity and the process for preparing the same TANABE SEIYAKU CO., LTD. (JP) 1998-12-15 US disclosed
EP-0790240-A1 Phenol-derivatives having pharmaceutical activity and process for preparing the same TANABE SEIYAKU CO., LTD. (JP) 1997-08-20 EP disclosed
US-5399623-A Semiconductors with sealing rubbers DAIKIN INDUSTRIES, LTD. (JP) 1995-03-21 US disclosed
EP-0607457-A1 VULCANIZING FLUORORUBBER COMPOSITION DAIKIN INDUSTRIES, LTD. (JP) 1994-07-27 EP disclosed
EP-0259303-B1 FOG SUPPRESSANT FOR PHOTOTHERMOGRAPHIC IMAGING COMPOSITIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-08-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240383849-A1 CO-CRYSTAL OR SALT SLC6A3, SLC6A2, OPRK1 ALDH1A1 4473/4885HSD17B10 1877/4885ALOX15 3619/4885
US-12060328-B2 Co-crystals or salts of psilocybin and methods of treatment therewith SLC6A3, SLC6A2, HTR2B ALDH1A1 4504/4885HSD17B10 1938/4885ALOX15 3905/4885
US-20230279032-A1 CO-CRYSTAL OR SALT SLC6A3, SLC6A2, OPRK1 ALDH1A1 4473/4885HSD17B10 1877/4885ALOX15 3619/4885
US-12559458-B2 Co-crystals or salts of psilocin and methods of treatment therewith SLC6A2, SLC6A4, SLC6A3 ALDH1A1 2183/4885HSD17B10 1577/4885ALOX15 4082/4885
US-20230202978-A1 CO-CRYSTAL OR SALT SLC6A3, SLC6A2, SLC6A4 ALDH1A1 3987/4885HSD17B10 1857/4885ALOX15 4148/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.