Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5081002 | 0.83 | — | — | |
| SCHEMBL5087247 | 0.79 | ADRA2A (0.30) | ADRA2AADRA2BADRA2C | |
| SCHEMBL4724808 | 0.79 | APP (0.46) | KDM4ENPC1ALDH1A1TSHRHSD17B10 | |
| SCHEMBL5081008 | 0.77 | KDM4E (0.40) | KCNN4KDM4EALDH1A1 | |
| SCHEMBL5087245 | 0.72 | CYP1A2 (0.35) | KDM4E | |
| SCHEMBL4723561 | 0.72 | ALDH1A1 (0.40) | KDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL5083181 | 0.69 | KDM4E (0.41) | KCNN4KDM4ENPC1ALDH1A1 | |
| SCHEMBL558023 | 0.66 | KDM4E (0.38) | KDM4ENPC1ALDH1A1 | |
| SCHEMBL21222937 | 0.65 | MCHR1 (0.42) | ALDH1A1HSD17B10 | |
| SCHEMBL4721825 | 0.64 | NISCH (0.37) | KDM4ENPC1ALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375081-B2 | Therapeutic combination of a pneumocandin derivative and an antifungal agent | ASTELLAS PHARMA INC. (JP) | 2008-05-20 | — | — | US | claimed |
| US-6875740-B1 | Combination of a cyclic hexapeptide with antifungal drugs for treatment of fungal pathogens | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2005-04-05 | — | — | US | claimed |