SCHEMBL5083260

SCHEMBL5083260

Cc1cc(C)c2cccc(O)c2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 5/20 0.48
CYP2A6 P11509 2/20 0.48
HSD17B1 P14061 1/20 0.46
HSD17B2 P37059 1/20 0.46
TDP1 Q9NUW8 2/20 0.43
TRPA1 O75762 2/20 0.43
TP53 P04637 1/20 0.43
APP P05067 1/20 0.43
MAPT P10636 1/20 0.43
THRB P10828 1/20 0.43
HPGD P15428 1/20 0.43
ALOX15 P16050 1/20 0.43
TSHR P16473 1/20 0.43
CASP1 P29466 1/20 0.43
SNCA P37840 1/20 0.43
RECQL P46063 1/20 0.43
HSD17B10 Q99714 1/20 0.43
ATM Q13315 1/20 0.43
LMNA P02545 1/20 0.42
HTT P42858 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30365067 1.00 CYP1A2 (0.48) CYP1A2CYP2A6HSD17B1HSD17B2TDP1
SCHEMBL28942910 0.88 TRPA1 (0.42) CYP1A2CYP2A6HSD17B1HSD17B2TDP1
SCHEMBL9232253 0.84 LMNA (0.48) CYP1A2TDP1TRPA1APPMAPT
SCHEMBL598262 0.79 CYP1A2 (0.65) CYP1A2CYP2A6MAPTHPGDTSHR
SCHEMBL29595379 0.79 CYP1A2 (0.65) CYP1A2CYP2A6MAPTHPGDTSHR
SCHEMBL1101882 0.77 CYP1A2 (0.68) CYP1A2CYP2A6HSD17B1HSD17B2TDP1
SCHEMBL7043669 0.76 LMNA (0.46) CYP1A2HSD17B1HSD17B2TDP1TRPA1
SCHEMBL7046849 0.76 TRPA1 (0.39) CYP1A2CYP2A6HSD17B1HSD17B2TDP1
SCHEMBL7049718 0.76 GABRA1 (0.42) CYP1A2TDP1APPMAPTTHRB
SCHEMBL598737 0.76 CYP1A2 (0.59) CYP1A2CYP2A6TDP1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120205822-A1 RESIN COMPOSITION FOR ENCAPSULATING SEMICONDUCTOR AND SEMICONDUCTOR DEVICE USING THE RESIN COMPOSITION SUMITOMO BAKELITE CO., LTD. (JP) 2012-08-16 US disclosed
US-20080314294-A1 Petroleum Asphalts Modified by Liquefied Biomass Additives WHITE DONALD H 2008-12-25 US disclosed
CN-1211336-C High-quality bisphenol A and process for producing the same MITSUI CHEMICALS INC (JP) 2005-07-20 CN disclosed
US-20030212168-A1 Petroleum asphalts modified by liquefied biomass additives WHITE DONALD H (US) 2003-11-13 US disclosed
US-20030028055-A1 High quality bisphenol a and preparation process thereof MITSUI CHEMICALS, INC. (JP) 2003-02-06 US disclosed
CN-1345297-A High-quality bisphenol A and process for producing the same MITSUI CHEMICALS INC (JP) 2002-04-17 CN disclosed
EP-1149816-A1 HIGH-QUALITY BISPHENOL A AND PROCESS FOR PRODUCING THE SAME Mitsui Chemicals, Inc. (JP) 2001-10-31 EP disclosed
WO-2001059008-A1 PETROLEUM ASPHALTS MODIFIED BY LIQUEFIED BIOMASS ADDITIVES WASTE TECHNOLOGY TRANSFER, INC. (US) 2001-08-16 WO disclosed
US-5916826-A COAL PELLET MIXTURE COMPRISES A BIO-BINDER BASE OBTAINED BY DIRECT LIQUEFACTION OF CELLULOSE BIO-MATERIAL AND COAL FINES WASTE TECHNOLOGY TRANSFER, INC. (US) 1999-06-29 US disclosed
WO-1999029812-A1 COAL BINDER PRODUCED BY LIQUEFACTION OF BIOMASS WASTE TECHNOLOGY TRANSFER, INC. (US) 1999-06-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030028055-A1 High quality bisphenol a and preparation process thereof TET2, PCBP1, PAH CYP1A2 307/4885CYP2A6 606/4885HSD17B1 1965/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.