Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27946667 | 0.88 | ALDH1A1 (0.54) | ALDH1A1HTR1BTRPA1GABRA1GABRB2 | |
| SCHEMBL4887288 | 0.81 | LMNA (0.53) | ALDH1A1MAPTLMNAGAATDP1 | |
| SCHEMBL6858603 | 0.81 | CYP1A2 (0.50) | ALDH1A1HTR1BTRPA1MAPTLMNA | |
| SCHEMBL11103978 | 0.81 | HTR1B (0.62) | ALDH1A1HTR1BMAPTLMNAGAA | |
| SCHEMBL73523 | 0.80 | TDP1 (0.53) | ALDH1A1MAPTLMNATDP1KDM4E | |
| SCHEMBL27593666 | 0.80 | HTR1B (0.50) | ALDH1A1HTR1BTRPA1MAPTLMNA | |
| SCHEMBL1264523 | 0.79 | CA2 (0.53) | ALDH1A1GABRA1GABRB2MAPTLMNA | |
| SCHEMBL11287144 | 0.79 | MEN1 (0.50) | ALDH1A1MAPTLMNAKMT2ACYP2C19 | |
| SCHEMBL9191426 | 0.79 | ALDH1A1 (0.52) | ALDH1A1TRPA1GABRA1GABRB2MAPT | |
| SCHEMBL15779795 | 0.77 | ALDH1A1 (0.50) | ALDH1A1HTR1BTRPA1GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0319986-B1 | Anti-plasmin depressant | NIPPON SHINYAKU CO LTD (JP) | 1997-03-12 | — | — | EP | claimed |
| EP-1792940-B1 | ACRYLIC SOL COMPOSITION | ADEKA CORP (JP) | 2008-10-22 | — | — | EP | disclosed |
| US-20070251415-A1 | Acrylic Sol Composition | ADEKA CORPORATION (JP) | 2007-11-01 | — | — | US | disclosed |
| EP-1792940-A1 | ACRYLIC SOL COMPOSITION | Adeka Corporation (JP) | 2007-06-06 | — | — | EP | disclosed |
| EP-0319986-B1 | Anti-plasmin depressant | NIPPON SHINYAKU CO LTD (JP) | 1997-03-12 | — | — | EP | disclosed |