SCHEMBL5083428

SCHEMBL5083428

CCOC(=O)C(C(CC)OC(=O)c1ccccc1)C(C)(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
NPC1 O15118 3/20 0.46
LMNA P02545 1/20 0.43
PRKCA P17252 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
RAB9A P51151 2/20 0.42
GAA P10253 1/20 0.42
TSHR P16473 3/20 0.41
TP53 P04637 1/20 0.41
TDP1 Q9NUW8 2/20 0.41
CYP2D6 P10635 2/20 0.41
HTR1A P08908 1/20 0.41
SCN1A P35498 1/20 0.41
SLC6A3 Q01959 1/20 0.41
SCN5A Q14524 1/20 0.41
SCN2A Q99250 1/20 0.41
SCN3A Q9NY46 1/20 0.41
ADRB2 P07550 1/20 0.41
ADRB1 P08588 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5079869 0.89 LMNA (0.44) MEN1KMT2ANPC1LMNAPRKCA
SCHEMBL5082872 0.84 MEN1 (0.47) MEN1KMT2ANPC1LMNASMN1; SMN2
SCHEMBL5083416 0.82 NPC1 (0.47) MEN1KMT2ANPC1LMNAPRKCA
SCHEMBL888330 0.81 NPC1 (0.49) MEN1KMT2ANPC1LMNAPRKCA
SCHEMBL5085898 0.81 NPC1 (0.49) MEN1KMT2ANPC1LMNAPRKCA
SCHEMBL9856444 0.80 MEN1 (0.47) MEN1KMT2ANPC1LMNAPRKCA
SCHEMBL12863873 0.79 TSHR (0.52) MEN1KMT2ANPC1LMNAPRKCA
SCHEMBL5082118 0.78 LMNA (0.44) MEN1KMT2ANPC1LMNASMN1; SMN2
SCHEMBL5082111 0.78 LMNA (0.44) MEN1KMT2ANPC1LMNASMN1; SMN2
SCHEMBL5085827 0.78 LMNA (0.46) MEN1KMT2ANPC1LMNAPRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1746110-B1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION REACTION AND CATALYST THEREOF CHINA PETROLEUM & CHEMICAL (CN) 2015-03-11 EP disclosed
US-7351778-B2 Catalyst component for olefin polymerization and catalyst comprising the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-04-01 US disclosed
EP-1746110-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION REACTION AND CATALYST THEREOF China Petroleum & Chemical Corporation (CN) 2007-01-24 EP disclosed
US-20060287446-A1 Catalyst component for olefin polymerization and catalyst comprising the same BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CHINA PETROLEUM & CHEMICAL COPORATION (CN) 2006-12-21 US disclosed