SCHEMBL5085827

SCHEMBL5085827

CCCC(C(=O)OCC)C(CC)OC(=O)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
NPC1 O15118 3/20 0.46
POLB P06746 1/20 0.45
PRKCA P17252 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
GAA P10253 2/20 0.42
RAB9A P51151 2/20 0.42
TSHR P16473 2/20 0.41
TP53 P04637 1/20 0.41
PIN1 Q13526 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
ALDH1A1 P00352 4/20 0.40
MAPT P10636 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5085964 0.93 LMNA (0.47) LMNAMEN1KMT2ANPC1POLB
SCHEMBL5086230 0.92 MEN1 (0.44) LMNAMEN1KMT2ANPC1POLB
SCHEMBL5085898 0.90 NPC1 (0.49) LMNAMEN1KMT2ANPC1PRKCA
SCHEMBL5082885 0.89 LMNA (0.46) LMNAMEN1KMT2ANPC1POLB
SCHEMBL5941243 0.87 TSHR (0.49) LMNAMEN1KMT2ANPC1PRKCA
SCHEMBL5082210 0.86 MEN1 (0.44) LMNAMEN1KMT2ANPC1POLB
SCHEMBL5079895 0.85 KMT2A (0.44) LMNAMEN1KMT2ANPC1PRKCA
SCHEMBL5082107 0.85 MMP8 (0.47) LMNAMEN1KMT2ANPC1PRKCA
SCHEMBL5082861 0.84 LMNA (0.47) LMNAMEN1KMT2ANPC1POLB
SCHEMBL5082873 0.83 MEN1 (0.43) LMNAMEN1KMT2ANPC1PRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1690039-A Diester compound for preparing olefinic polymerization catalyst SINOPEC CORP (CN) 2005-11-02 CN claimed
EP-1746110-B1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION REACTION AND CATALYST THEREOF CHINA PETROLEUM & CHEMICAL (CN) 2015-03-11 EP disclosed
CN-101759816-B Method for preparing a catalyst component for olefinic polymerization, and a catalyst component thereof CHINA PETROLEUM & CHEMICAL 2012-05-30 CN disclosed
CN-101759816-A Method for preparing a catalyst component for olefinic polymerization, and a catalyst component thereof CHINA PETROLEUM & CHEMICAL 2010-06-30 CN disclosed
CN-100429243-C Method for preparing catalyst constituent for olefinic polymerization CHINA PETROCHEMICAL CO LTD (CN) 2008-10-29 CN disclosed
CN-100429242-C Catalyst components for olefinic polyreaction and catalyst thereof CHINA PETROLEUM & CHEMICAL (CN) 2008-10-29 CN disclosed
US-7351778-B2 Catalyst component for olefin polymerization and catalyst comprising the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-04-01 US disclosed
CN-100348624-C Catalyst components for olefinic polyreaction and catalyst thereof CHINA PETROLEUM & CHEMICAL (CN) 2007-11-14 CN disclosed
EP-1746110-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION REACTION AND CATALYST THEREOF China Petroleum & Chemical Corporation (CN) 2007-01-24 EP disclosed
CN-1891722-A Method for preparing catalyst constituent for olefinic polymerization CHINA PETROCHEMICAL CO LTD (CN) 2007-01-10 CN disclosed
CN-1282670-C Catalyst components for olefinic polyreaction and catalyst thereof CHINA PETROLEUM & CHEMICAL (CN) 2006-11-01 CN disclosed
CN-1803863-A Catalyst components for olefinic polyreaction and catalyst thereof CHINA PETROLEUM & CHEMICAL (CN) 2006-07-19 CN disclosed
CN-1803862-A Catalyst components for olefinic polyreaction and catalyst thereof CHINA PETROLEUM & CHEMICAL (CN) 2006-07-19 CN disclosed
CN-1690090-A Catalyst components for olefinic polyreaction and catalyst thereof SINOPEC CORP (CN) 2005-11-02 CN disclosed
CN-1690039-A Diester compound for preparing olefinic polymerization catalyst SINOPEC CORP (CN) 2005-11-02 CN disclosed