Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 18/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5079844 | 1.00 | GPR119 (0.43) | GPR119RORCKCNH2PIK3CAMTOR | |
| SCHEMBL3986020 | 1.00 | GPR119 (0.43) | GPR119RORCKCNH2PIK3CAMTOR | |
| SCHEMBL14191007 | 0.89 | GPR119 (0.55) | GPR119 | |
| SCHEMBL14218038 | 0.89 | GPR119 (0.55) | GPR119 | |
| SCHEMBL14191008 | 0.89 | GPR119 (0.55) | GPR119 | |
| SCHEMBL3984054 | 0.86 | GPR119 (0.48) | GPR119RORCKCNH2PIK3CAMTOR | |
| SCHEMBL3980543 | 0.82 | F2R (0.40) | GPR119 | |
| SCHEMBL3981032 | 0.81 | GPR119 (0.42) | GPR119PIK3CAMTOR | |
| SCHEMBL3980193 | 0.80 | GPR119 (0.50) | GPR119RORCKCNH2PIK3CAMTOR | |
| SCHEMBL3983937 | 0.79 | GPR119 (0.47) | GPR119RORCKCNH2PIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080103123-A1 | New compounds | BIOVITRUM (SE) | 2008-05-01 | — | — | US | claimed |
| US-20080103123-A1 | New compounds | BIOVITRUM (SE) | 2008-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080103123-A1 | New compounds | GPR119, GPR139, GPR180 | GPR119 1/4885RORC 154/4885KCNH2 1859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.