SCHEMBL5083529

SCHEMBL5083529

FC(F)(F)c1ccc(O[Zr](Oc2ccc(C(F)(F)F)cc2)(C2C=Cc3ccccc32)=[Si](Cc2ccccc2)Cc2ccccc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.36
PPARA Q07869 1/20 0.36
AR P10275 1/20 0.33
CYP19A1 P11511 1/20 0.31
CYP11B1 P15538 1/20 0.31
CYP11B2 P19099 1/20 0.31
SIGMAR1 Q99720 2/20 0.31
MRGPRX4 Q96LA9 1/20 0.31
SLC6A2 P23975 4/20 0.30
SLC6A4 P31645 4/20 0.30
MAPK14 Q16539 1/20 0.30
SLC6A3 Q01959 2/20 0.30
KCNK2 O95069 1/20 0.30
KCNH2 Q12809 1/20 0.30
CACNA1C Q13936 1/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5494485 0.83 PPARG (0.31) PPARGPPARAALDH1A1
SCHEMBL5496106 0.71 PPARG (0.34) PPARGPPARAARSIGMAR1MRGPRX4
SCHEMBL5083540 0.66 PPARG (0.35) PPARGPPARAARSIGMAR1MRGPRX4
SCHEMBL5496111 0.65 PPARG (0.34) PPARGPPARAARSIGMAR1MRGPRX4
SCHEMBL14011235 0.62 SLC6A2 (0.38) PPARGPPARACYP11B1CYP11B2SLC6A2
SCHEMBL7645058 0.62 SLC6A2 (0.38) PPARGPPARACYP11B1CYP11B2SLC6A2
SCHEMBL4862205 0.62 SLC6A2 (0.38) PPARGPPARACYP11B1CYP11B2SLC6A2
SCHEMBL5081435 0.62 ALDH1A1 (0.33) SLC6A2SLC6A4ALDH1A1
SCHEMBL6055286 0.62 SIGMAR1 (0.39) SIGMAR1SLC6A2SLC6A3KCNH2MEN1
SCHEMBL5273072 0.62 SIGMAR1 (0.39) SIGMAR1SLC6A2SLC6A3KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7345119-B2 Olefin polymerization catalyst and olefin polymerization method using the same MARUZEN PETROCHEMICAL COMPANY, LIMITED (JP) 2008-03-18 US disclosed
US-20050215736-A1 Olefin polymerization catalyst and olefin polymerization method using the same MARUZEN PETROCHEMICAL COMPANY, LIMITED (JP) 2005-09-29 US disclosed
EP-1541598-A1 Olefin polymerization catalyst and olefin polymerization method using the same MARUZEN PETROCHEMICAL CO., LTD. (JP) 2005-06-15 EP disclosed