SCHEMBL5083540

SCHEMBL5083540

FC(F)(F)c1ccc(O[Zr](=[SiH2])(Cc2ccccc2)(Cc2ccccc2)(Oc2ccc(C(F)(F)F)cc2)C2C=Cc3ccccc32)cc1

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.35
PPARA Q07869 1/20 0.35
MAPK14 Q16539 2/20 0.33
SIGMAR1 Q99720 5/20 0.32
AR P10275 1/20 0.32
MRGPRX4 Q96LA9 1/20 0.32
SLC6A2 P23975 4/20 0.31
SLC6A4 P31645 4/20 0.31
SLC6A3 Q01959 2/20 0.31
KCNK2 O95069 1/20 0.31
KCNH2 Q12809 1/20 0.31
CACNA1C Q13936 1/20 0.31
LMNA P02545 1/20 0.31
SLC6A5 Q9Y345 1/20 0.31
CNR2 P34972 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5494488 0.80 SLC6A2 (0.33) SIGMAR1SLC6A2SLC6A4SLC6A3KCNK2
SCHEMBL5496111 0.71 PPARG (0.34) PPARGPPARAMAPK14SIGMAR1AR
SCHEMBL4445239 0.71 SIGMAR1 (0.37) SIGMAR1
SCHEMBL5496106 0.68 PPARG (0.34) PPARGPPARAMAPK14SIGMAR1AR
Hydrochloric Acid SCHEMBL7772298 0.67 SIGMAR1 (0.39) SIGMAR1SLC6A2SLC6A3KCNH2LMNA
SCHEMBL5083529 0.66 PPARG (0.36) PPARGPPARAMAPK14SIGMAR1AR
SCHEMBL5081437 0.64 KIF11 (0.34) SLC6A2SLC6A4
SCHEMBL7645058 0.64 SLC6A2 (0.38) PPARGPPARASLC6A2SLC6A4
SCHEMBL4862205 0.64 SLC6A2 (0.38) PPARGPPARASLC6A2SLC6A4
SCHEMBL14011235 0.64 SLC6A2 (0.38) PPARGPPARASLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7345119-B2 Olefin polymerization catalyst and olefin polymerization method using the same MARUZEN PETROCHEMICAL COMPANY, LIMITED (JP) 2008-03-18 US disclosed
US-20050215736-A1 Olefin polymerization catalyst and olefin polymerization method using the same MARUZEN PETROCHEMICAL COMPANY, LIMITED (JP) 2005-09-29 US disclosed
EP-1541598-A1 Olefin polymerization catalyst and olefin polymerization method using the same MARUZEN PETROCHEMICAL CO., LTD. (JP) 2005-06-15 EP disclosed