SCHEMBL5083571

SCHEMBL5083571

CC(=O)c1cc(S(=O)(=O)O)ccc1C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.49
KDM4E B2RXH2 2/20 0.49
HSD17B10 Q99714 2/20 0.49
HPGD P15428 1/20 0.49
GAA P10253 1/20 0.42
TSHR P16473 1/20 0.42
PHLPP2 Q6ZVD8 1/20 0.42
HTT P42858 1/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA12 O43570 1/20 0.41
CA7 P43166 1/20 0.41
CA14 Q9ULX7 1/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
S1PR3 Q99500 1/20 0.40
SNCA P37840 1/20 0.40
CASP6 P55212 1/20 0.40
POLB P06746 1/20 0.39
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8862312 0.85 KDM4E (0.62) ALDH1A1KDM4EHSD17B10HPGDGAA
SCHEMBL29543150 0.85 KDM4E (0.62) ALDH1A1KDM4EHSD17B10HPGDGAA
SCHEMBL15836210 0.85 LMNA (0.51) ALDH1A1KDM4EGAATSHRHTT
SCHEMBL312086 0.85 HSD17B10 (0.68) ALDH1A1KDM4EHSD17B10HPGDTSHR
Ammonia Solution, Strong SCHEMBL7644798 0.83 HSD17B10 (0.66) ALDH1A1KDM4EHSD17B10HPGDTSHR
SCHEMBL1805024 0.83 MAPK1 (0.55) ALDH1A1KDM4EHSD17B10HPGDGAA
SCHEMBL8747770 0.83 KDM4E (0.47) ALDH1A1KDM4EHSD17B10HPGDGAA
SCHEMBL1805021 0.83 ALDH1A1 (0.47) ALDH1A1KDM4EHSD17B10HPGDGAA
Ammonia Solution, Strong SCHEMBL7644790 0.83 HSD17B10 (0.66) ALDH1A1KDM4EHSD17B10HPGDTSHR
SCHEMBL10866650 0.83 KDM4E (0.61) ALDH1A1KDM4EHSD17B10HPGDGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4170566-A BLEACHES FMC CORPORATION (US) 1979-10-09 US claimed
US-4110074-A Mixed carboxylic/sulfonic anhydrides in peroxygen bleaching FMC CORPORATION (US) 1978-08-29 US claimed
CN-107250174-B High pressure free radical polymerization process for copolymers of ethylene and silane group-containing comonomers 博里利斯股份公司 2020-12-25 CN disclosed
CN-107256730-B Semiconductive polyolefin composition containing epoxy groups 博里利斯股份公司 2019-12-27 CN disclosed
EP-1718599-A4 SYNTHESIS OF STERICALLY HINDERED SECONDARY AMINOETHER ALCOHOLS EXXONMOBIL RES & ENG CO (US) 2008-06-25 EP disclosed
EP-1718599-A1 SYNTHESIS OF STERICALLY HINDERED SECONDARY AMINOETHER ALCOHOLS ExxonMobil Research and Engineering Company (US) 2006-11-08 EP disclosed
WO-2005082835-A1 SYNTHESIS OF STERICALLY HINDERED SECONDARY AMINOETHER ALCOHOLS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2005-09-09 WO disclosed
EP-0023785-B1 QUINOXALINYLOXYPHENOXYALKANE CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS HERBICIDES ICI AUSTRALIA LIMITED (AU) 1985-04-03 EP disclosed
US-4170566-A BLEACHES FMC CORPORATION (US) 1979-10-09 US disclosed
US-4110074-A Mixed carboxylic/sulfonic anhydrides in peroxygen bleaching FMC CORPORATION (US) 1978-08-29 US disclosed