SCHEMBL8747770

SCHEMBL8747770

Cc1ccc(S(=O)(=O)O)cc1C(=O)Cl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.47
ALDH1A1 P00352 2/20 0.47
HSD17B10 Q99714 2/20 0.47
HPGD P15428 1/20 0.47
GAA P10253 1/20 0.41
TSHR P16473 1/20 0.41
PHLPP2 Q6ZVD8 1/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
S1PR3 Q99500 1/20 0.39
FLT1 P17948 1/20 0.39
FLT4 P35916 1/20 0.39
KDR P35968 1/20 0.39
SNCA P37840 1/20 0.39
LMNA P02545 1/20 0.39
POLB P06746 2/20 0.38
MAPK1 P28482 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CA2 P00918 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15575808 0.85 LMNA (0.39) KDM4EALDH1A1GAATSHRMEN1
SCHEMBL11183735 0.84 POLB (0.48) KDM4EGAAMEN1KMT2APOLB
SCHEMBL28137838 0.84 ALDH1A1 (0.42) KDM4EALDH1A1HSD17B10HPGDGAA
SCHEMBL5083571 0.83 ALDH1A1 (0.49) KDM4EALDH1A1HSD17B10HPGDGAA
SCHEMBL8862312 0.83 KDM4E (0.62) KDM4EALDH1A1HSD17B10HPGDGAA
SCHEMBL29543150 0.83 KDM4E (0.62) KDM4EALDH1A1HSD17B10HPGDGAA
SCHEMBL1805024 0.81 MAPK1 (0.55) KDM4EALDH1A1HSD17B10HPGDGAA
SCHEMBL1805021 0.81 ALDH1A1 (0.47) KDM4EALDH1A1HSD17B10HPGDGAA
SCHEMBL10866650 0.81 KDM4E (0.61) KDM4EALDH1A1HSD17B10HPGDGAA
SCHEMBL11179145 0.81 SMN1; SMN2 (0.54) KDM4EALDH1A1GAAKMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0459950-B1 Stabilisation of dyes on polyamide fibres CIBA GEIGY AG (CH) 1997-03-12 EP disclosed
EP-0438381-B1 Stabilization of dyes on polyamide fibres CIBA GEIGY AG (CH) 1995-04-05 EP disclosed
US-5356443-A Treating fiber before fixation step with sterically hindered phenol and sulfo containing compound CIBA-GEIGY CORPORATION (US) 1994-10-18 US disclosed
US-5181935-A THERMAL AND PHOTOCHEMICAL STABILIZATION OF DYEINGS ON POLYAMIDE FIBERS:STERICALLY HINDERED PHENOL AND ULTRA-VIOLET ABSORBER CIBA-GEIGY CORPORATION (US) 1993-01-26 US disclosed
US-5096456-A Exhaust or continuous dyeing; carpets automotive fabrics, brassiers CIBA-GEIGY CORPORATION (US) 1992-03-17 US disclosed
EP-0459950-A1 Stabilisation of dyes on polyamide fibres CIBA-GEIGY AG (CH) 1991-12-04 EP disclosed
EP-0438381-A1 Stabilization of dyes on polyamide fibres CIBA-GEIGY AG (CH) 1991-07-24 EP disclosed