Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 10/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Naphthalene SCHEMBL5080748 | 0.82 | TSHR (0.61) | CYP2A6TDP1CYP1A2ALDH1A1TSHR | |
| Chloromethane SCHEMBL28810553 | 0.80 | CYP2A6 (0.90) | CYP2A6TDP1CYP1A2ALDH1A1TSHR | |
| SCHEMBL29372904 | 0.79 | CYP2A6 (1.00) | CYP2A6TDP1CYP1A2ALDH1A1TSHR | |
| SCHEMBL28081333 | 0.79 | CYP2A6 (1.00) | CYP2A6TDP1CYP1A2ALDH1A1TSHR | |
| SCHEMBL36453 | 0.79 | CYP2A6 (1.00) | CYP2A6TDP1CYP1A2ALDH1A1TSHR | |
| SCHEMBL5084368 | 0.79 | CYP2A6 (0.65) | CYP2A6TDP1CYP1A2ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL7988310 | 0.77 | CYP2A6 (0.94) | CYP2A6TDP1CYP1A2ALDH1A1TSHR | |
| SCHEMBL10886086 | 0.77 | CYP2A6 (0.94) | CYP2A6TDP1CYP1A2ALDH1A1TSHR | |
| Methane SCHEMBL16096368 | 0.77 | CYP2A6 (0.94) | CYP2A6TDP1CYP1A2ALDH1A1TSHR | |
| Ethane SCHEMBL11323050 | 0.77 | CYP2A6 (0.94) | CYP2A6TDP1CYP1A2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8076375-B2 | Methods of inhibiting poxvirus growth | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2011-12-13 | — | — | US | disclosed |
| US-20080306031-A1 | Methods of Inhibiting Poxvirus Growth | SALK INSTITUTE FOR BIOLOGICAL STUDIES | 2008-12-11 | — | — | US | disclosed |
| WO-2007047339-A2 | METHODS OF INHIBITING POXVIRUS GROWTH | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2007-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306031-A1 | Methods of Inhibiting Poxvirus Growth | TTK, TXK, DCK | CYP2A6 4109/4885TDP1 3150/4885CYP1A2 4590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.