Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Naphthalene SCHEMBL5080748 | 0.83 | TSHR (0.61) | CYP2A6ALDH1A1TDP1TSHRHIF1A | |
| SCHEMBL154221 | 0.81 | CYP2A6 (1.00) | CYP2A6ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL29485684 | 0.81 | CYP2A6 (1.00) | CYP2A6ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL5083606 | 0.79 | CYP2A6 (0.63) | CYP2A6ALDH1A1TDP1TSHRHIF1A | |
| SCHEMBL1120140 | 0.79 | CYP2A6 (0.94) | CYP2A6ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL22909955 | 0.79 | CYP2A6 (0.94) | CYP2A6ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL29002798 | 0.79 | CYP2A6 (0.94) | CYP2A6ALDH1A1TDP1MEN1KMT2A | |
| Benzene SCHEMBL27861653 | 0.79 | CYP2A6 (0.94) | CYP2A6ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL9727032 | 0.78 | CYP2A6 (0.74) | CYP2A6ALDH1A1TDP1MEN1KMT2A | |
| Formaldehyde SCHEMBL28823619 | 0.74 | CYP2A6 (0.85) | CYP2A6ALDH1A1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8076375-B2 | Methods of inhibiting poxvirus growth | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2011-12-13 | — | — | US | disclosed |
| US-20080306031-A1 | Methods of Inhibiting Poxvirus Growth | SALK INSTITUTE FOR BIOLOGICAL STUDIES | 2008-12-11 | — | — | US | disclosed |
| WO-2007047339-A2 | METHODS OF INHIBITING POXVIRUS GROWTH | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2007-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306031-A1 | Methods of Inhibiting Poxvirus Growth | TTK, TXK, DCK | CYP2A6 4109/4885ALDH1A1 4581/4885TDP1 3150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.