Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | CYP2A6 | P11509 | 6/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.31 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.31 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5084368 | 0.83 | CYP2A6 (0.65) | TSHRTDP1ALDH1A1HIF1ACYP2A6 | |
| SCHEMBL5083606 | 0.82 | CYP2A6 (0.63) | TSHRTDP1ALDH1A1HIF1ACYP2A6 | |
| SCHEMBL165983 | 0.78 | ALDH1A1 (1.00) | TSHRTDP1ALDH1A1HIF1AMEN1 | |
| Hydrochloric Acid SCHEMBL10715580 | 0.75 | ALDH1A1 (0.92) | TSHRTDP1ALDH1A1HIF1AMEN1 | |
| SCHEMBL9720387 | 0.75 | ALDH1A1 (0.92) | TSHRTDP1ALDH1A1HIF1AMEN1 | |
| Cyclooctane SCHEMBL3271413 | 0.69 | ALDH1A1 (0.79) | TSHRTDP1ALDH1A1HIF1AMEN1 | |
| Perchlorobenzene SCHEMBL10624049 | 0.68 | CYP2A6 (0.67) | TSHRTDP1ALDH1A1CYP2A6ALOX12 | |
| Naphthalene SCHEMBL8953 | 0.67 | CYP2A6 (1.00) | TSHRTDP1ALDH1A1HIF1ACYP2A6 | |
| Naphthalene SCHEMBL1332240 | 0.67 | CYP2A6 (1.00) | TSHRTDP1ALDH1A1HIF1ACYP2A6 | |
| SCHEMBL128887 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8076375-B2 | Methods of inhibiting poxvirus growth | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2011-12-13 | — | — | US | disclosed |
| US-20080306031-A1 | Methods of Inhibiting Poxvirus Growth | SALK INSTITUTE FOR BIOLOGICAL STUDIES | 2008-12-11 | — | — | US | disclosed |
| WO-2007047339-A2 | METHODS OF INHIBITING POXVIRUS GROWTH | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2007-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306031-A1 | Methods of Inhibiting Poxvirus Growth | TTK, TXK, DCK | TSHR 2784/4885TDP1 3150/4885ALDH1A1 4581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.