Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | TTR | P02766 | 2/20 | 0.43 |
| ▸ | ALB | P02768 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29413290 | 1.00 | CA12 (0.55) | CA12CA9CA1TTRALB | |
| SCHEMBL29320329 | 0.83 | GRM5 (0.45) | CA12CA9CA1GRM5 | |
| SCHEMBL214163 | 0.82 | CA12 (0.52) | CA12CA9TTRALBMEN1 | |
| SCHEMBL56741 | 0.82 | GRM5 (0.43) | TTRALBMEN1KMT2AGRM5 | |
| SCHEMBL509092 | 0.82 | CA12 (0.52) | CA12CA9TTRALBMEN1 | |
| SCHEMBL9264989 | 0.82 | CA12 (0.52) | CA12CA9TTRALBMEN1 | |
| SCHEMBL1421650 | 0.82 | GRM5 (0.47) | GRM5 | |
| SCHEMBL16958479 | 0.76 | CA12 (0.55) | CA12CA9CA1HCAR1 | |
| SCHEMBL2813175 | 0.76 | CA12 (0.55) | CA12CA9CA1HCAR1 | |
| Water SCHEMBL21493261 | 0.76 | CA9 (0.93) | CA12CA9CA1CA3CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 305 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12435034-B2 | Process of preparing 3-fluoro-5(((1R,2AR)-3,3,4,4-tetrafluoro-1,2A-dihydroxy-2,2A,3,4-tetrahydro-1H-cyclopenta[cd]inden-7-yl)-oxy)benzonitrile | NIKANG THERAPEUTICS, INC. (US) | 2025-10-07 | — | — | US | claimed |
| CN-115611847-B | Preparation method of Belzutifan intermediate | 南方科技大学坪山生物医药研究院 | 2024-04-30 | — | — | CN | claimed |
| EP-4229033-A1 | PROCESSES OF PREPARING 3-FLUORO-5-(((1S,2AR)-1,3,3,4,4-PENTAFLUORO-2A-HYDROXY-2,2A,3,4-TETRAHYDRO-1H-CYCLOPENTA[CD]INDEN-7-YL)OXY)-BENZONITRILE | Nikang Therapeutics, Inc. (US) | 2023-08-23 | — | — | EP | claimed |
| CN-116507601-A | Process for preparing 3-fluoro-5- (((1S, 2 aR) -1,3, 4-pentafluoro-2 a-hydroxy-2, 2a,3, 4-tetrahydro-1H-cyclopenta [ cd ] inden-7-yl) oxy) benzonitrile | 尼坎治疗公司 | 2023-07-28 | — | — | CN | claimed |
| US-20230202970-A1 | PROCESS OF PREPARING 3-FLUORO-5(((1R,2AR)-3,3,4,4-TETRAFLUORO-1,2A-DIHYDROXY-2,2A,3,4-TETRAHYDRO-1H-CYCLOPENTA[CD]INDEN-7-YL)-OXY)BENZONITRILE | NIKANG THERAPEUTIC INC (US) | 2023-06-29 | — | — | US | claimed |
| US-11634382-B2 | Process of preparing 3-fluoro-5(((1R,2aR)-3,3,4,4-tetrafluoro-1,2a-dihydroxy-2,2a,3,4-tetrahydro-1H-cyclopenta[cd]inden-7-yl)-oxy)benzonitrile | NIKANG THERAPEUTICS, INC. (US) | 2023-04-25 | — | — | US | claimed |
| CN-115611847-A | Preparation method of intermediate of Belzutifan | 南方科技大学坪山生物医药研究院 | 2023-01-17 | — | — | CN | claimed |
| WO-2022082329-A1 | PROCESSES OF PREPARING 3-FLUORO-5- ( ( (1S, 2AR) -1, 3, 3, 4, 4-PENTAFLUORO-2A-HYDROXY-2, 2A, 3, 4-TETRAHYDRO-1H-CYCLOPENTA [CD] INDEN-7-YL) OXY) -BENZONITRILE | NIKANG THERAPEUTICS, INC. (US) | 2022-04-28 | — | — | WO | claimed |
| WO-2022082337-A1 | PROCESS OF PREPARING 3-FLUORO-5 ( ( (1R, 2AR) -3, 3, 4, 4-TETRAFLUORO-1, 2A-DIHYDROXY-2, 2A, 3, 4-TETRAHYDRO-1H-CYCLOPENTA [CD] INDEN-7-YL) OXY) BENZONITRILE | NIKANG THERAPEUTICS, INC. (US) | 2022-04-28 | — | — | WO | claimed |
| WO-2022086822-A1 | PROCESSES OF PREPARING 3-FLUORO-5-(((1S,2AR)-1,3,3,4,4-PENTAFLUORO-2A-HYDROXY-2,2A,3,4-TETRAHYDRO-1H-CYCLOPENTA[CD]INDEN-7-YL)OXY)-BENZONITRILE | NIKANG THERAPEUTICS, INC. (US) | 2022-04-28 | — | — | WO | claimed |
| US-20220119345-A1 | PROCESS OF PREPARING 3-FLUORO-5(((1R,2AR)-3,3,4,4-TETRAFLUORO-1,2A-DIHYDROXY-2,2A,3,4-TETRAHYDRO-1H-CYCLOPENTA[CD]INDEN-7-YL)-OXY)BENZONITRILE | CHANGZHOU SYNTHEALL PHARMACEUTICAL CO., LTD (CN) | 2022-04-21 | — | — | US | claimed |
| CN-111162313-A | Polymer electrolyte and lithium ion battery | 珠海冠宇电池有限公司 | 2020-05-15 | — | — | CN | claimed |
| US-10029992-B2 | Diaminotriazine compounds and their use as herbicides | BASF SE (DE) | 2018-07-24 | — | — | US | claimed |
| EP-3134391-A1 | DIAMINOTRIAZINE COMPOUNDS AND THEIR USE AS HERBICIDES | BASF SE (DE) | 2017-03-01 | — | — | EP | claimed |
| US-20170044114-A1 | Diaminotriazine compounds and their use as herbicides | BASF SE (DE) | 2017-02-16 | — | — | US | claimed |
| WO-2015162166-A1 | DIAMINOTRIAZINE COMPOUNDS AND THEIR USE AS HERBICIDES | BASF SE (DE) | 2015-10-29 | — | — | WO | claimed |
| CN-122080069-A | Phospholipid compounds and uses thereof | — | 2026-05-26 | — | — | CN | disclosed |
| EP-3887359-B1 | NOVEL TETRAZINE COMPOUNDS FOR IN VIVO IMAGING | UNIV COPENHAGEN (DK) | 2026-05-06 | — | — | EP | disclosed |
| US-20030100554-A1 | Pyrazole derivatives | JONES LYN HOWARD (GB) | 2003-05-29 | — | — | US | disclosed |
| WO-2002085860-A1 | PYRAZOLE DERIVATIVES FOR TREATING HIV | PFIZER LIMITED (GB) | 2002-10-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11634382-B2 | Process of preparing 3-fluoro-5(((1R,2aR)-3,3,4,4-tetrafluoro-1,2a-dihydroxy-2,2a,3,4-tetrahydro-1H-cyclopenta[cd]inden-7-yl)-oxy)benzonitrile | CYP4B1, CYP1B1, CYP3A4 | CA12 2268/4885CA9 959/4885CA1 1250/4885 |
| US-20220119345-A1 | PROCESS OF PREPARING 3-FLUORO-5(((1R,2AR)-3,3,4,4-TETRAFLUORO-1,2A-DIHYDROXY-2,2A,3,4-TETRAHYDRO-1H-CYCLOPENTA[CD]INDEN-7-YL)-OXY)BENZONITRILE | CYP4B1, CYP1B1, CYP3A4 | CA12 2268/4885CA9 959/4885CA1 1250/4885 |
| US-20230202970-A1 | PROCESS OF PREPARING 3-FLUORO-5(((1R,2AR)-3,3,4,4-TETRAFLUORO-1,2A-DIHYDROXY-2,2A,3,4-TETRAHYDRO-1H-CYCLOPENTA[CD]INDEN-7-YL)-OXY)BENZONITRILE | CYP4B1, CYP1B1, CYP3A4 | CA12 2268/4885CA9 959/4885CA1 1250/4885 |
| US-12435034-B2 | Process of preparing 3-fluoro-5(((1R,2AR)-3,3,4,4-tetrafluoro-1,2A-dihydroxy-2,2A,3,4-tetrahydro-1H-cyclopenta[cd]inden-7-yl)-oxy)benzonitrile | CYP4B1, CYP1B1, CYP3A4 | CA12 2268/4885CA9 959/4885CA1 1250/4885 |
| US-10029992-B2 | Diaminotriazine compounds and their use as herbicides | NR4A3, CBR3, RCOR3 | CA12 2929/4885CA9 4092/4885CA1 965/4885 |
| US-20030100554-A1 | Pyrazole derivatives | REV1, SARS1, CYP2F1 | CA12 4864/4885CA9 4603/4885CA1 4635/4885 |
| US-20170044114-A1 | Diaminotriazine compounds and their use as herbicides | NR4A3, CBR3, RCOR3 | CA12 2954/4885CA9 4119/4885CA1 986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.