Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5252175 | 0.89 | TSHR (0.49) | TSHRHCAR2ALDH1A1TDP1GPR84 | |
| SCHEMBL28708751 | 0.86 | TSHR (0.40) | TSHRTHRBCASP1HCAR2GAA | |
| SCHEMBL5078362 | 0.86 | CASP1 (0.44) | TSHRTHRBCASP1GAAALDH1A1 | |
| SCHEMBL10954723 | 0.86 | TSHR (0.59) | TSHRHCAR2GPR84NAAAFFAR1 | |
| SCHEMBL6685570 | 0.84 | TSHR (0.38) | TSHRTHRBALDH1A1GPR84FFAR1 | |
| SCHEMBL2527545 | 0.82 | ALDH1A1 (0.41) | TSHRHDAC1HDAC2HDAC7HDAC8 | |
| SCHEMBL1593009 | 0.82 | TSHR (0.42) | TSHRTHRBCASP1HCAR2GAA | |
| SCHEMBL4653225 | 0.80 | TSHR (0.41) | TSHRTHRBCASP1HCAR2GAA | |
| SCHEMBL6685907 | 0.79 | TSHR (0.46) | TSHRHCAR2ALDH1A1GPR84NAAA | |
| SCHEMBL21638809 | 0.79 | TSHR (0.59) | TSHRHCAR2GPR84NAAAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1752475-B1 | Lactone ring-containing polymer having few foreign matters and not easily causing gelation, and its applications | NIPPON CATALYTIC CHEM IND (JP) | 2008-11-05 | — | — | EP | disclosed |
| US-20070037962-A1 | Lactone ring-containing polymer having few foreign matters and not easily causing gelation, and its applications | NIPPON SHOKUBAI CO., LTD. (JP) | 2007-02-15 | — | — | US | disclosed |
| EP-1752475-A1 | Lactone ring-containing polymer having few foreign matters and not easily causing gelation, and its applications | NIPPON SHOKUBAI CO., LTD. (JP) | 2007-02-14 | — | — | EP | disclosed |