Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16152888 | 0.89 | CASP1 (0.42) | CASP1ALDH1A1TSHRCYP2D6CYP2C19 | |
| SCHEMBL5084328 | 0.86 | TSHR (0.39) | CASP1ALDH1A1TSHRLMNAGAA | |
| SCHEMBL16152775 | 0.85 | GPR84 (0.52) | CASP1TSHR | |
| SCHEMBL16152902 | 0.85 | GPR84 (0.52) | CASP1TSHR | |
| SCHEMBL2527545 | 0.83 | ALDH1A1 (0.41) | ALDH1A1TSHRCYP2D6CYP2C19NPSR1 | |
| SCHEMBL5385552 | 0.83 | CASP1 (0.46) | CASP1ALDH1A1TSHRCYP2D6CYP2C19 | |
| SCHEMBL6677187 | 0.83 | CASP1 (0.41) | CASP1ALDH1A1TSHRCYP2D6CYP2C19 | |
| SCHEMBL5252175 | 0.83 | TSHR (0.49) | ALDH1A1TSHRNPSR1 | |
| SCHEMBL10954723 | 0.80 | TSHR (0.59) | TSHRNPSR1 | |
| SCHEMBL5084326 | 0.78 | LMNA (0.36) | TSHRNPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9527795-B2 | Methylene beta-ketoester monomers, methods for making methylene beta-ketoester monomers, polymerizable compositions and products formed therefrom | SIRRUS, INC. (US) | 2016-12-27 | — | — | US | disclosed |
| US-9527795-B2 | Methylene beta-ketoester monomers, methods for making methylene beta-ketoester monomers, polymerizable compositions and products formed therefrom | SIRRUS, INC. (US) | 2016-12-27 | — | — | US | disclosed |
| US-9073885-B2 | Vitamin D3 lactone derivatives | TEIJIN PHARMA LIMITED (JP) | 2015-07-07 | — | — | US | disclosed |
| US-9073885-B2 | Vitamin D3 lactone derivatives | TEIJIN PHARMA LIMITED (JP) | 2015-07-07 | — | — | US | disclosed |
| EP-1589009-B1 | VITAMIN D3 LACTONE DERIVATIVE | TEIJIN PHARMA LTD (JP) | 2014-10-08 | — | — | EP | disclosed |
| US-20140288230-A1 | METHYLENE BETA-KETOESTER MONOMERS, METHODS FOR MAKING METHYLENE BETA-KETOESTER MONOMERS, POLYMERIZABLE COMPOSITIONS AND PRODUCTS FORMED THEREFROM | SIRRUS, INC. | 2014-09-25 | — | — | US | disclosed |
| US-20140288230-A1 | METHYLENE BETA-KETOESTER MONOMERS, METHODS FOR MAKING METHYLENE BETA-KETOESTER MONOMERS, POLYMERIZABLE COMPOSITIONS AND PRODUCTS FORMED THEREFROM | SIRRUS, INC. | 2014-09-25 | — | — | US | disclosed |
| EP-1752475-B1 | Lactone ring-containing polymer having few foreign matters and not easily causing gelation, and its applications | NIPPON CATALYTIC CHEM IND (JP) | 2008-11-05 | — | — | EP | disclosed |
| EP-1832571-A1 | Process for producing hydroxyl group-containing vinyl compound | FUJIFILM Corporation (JP) | 2007-09-12 | — | — | EP | disclosed |
| US-20070037962-A1 | Lactone ring-containing polymer having few foreign matters and not easily causing gelation, and its applications | NIPPON SHOKUBAI CO., LTD. (JP) | 2007-02-15 | — | — | US | disclosed |
| EP-1752475-A1 | Lactone ring-containing polymer having few foreign matters and not easily causing gelation, and its applications | NIPPON SHOKUBAI CO., LTD. (JP) | 2007-02-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140288230-A1 | METHYLENE BETA-KETOESTER MONOMERS, METHODS FOR MAKING METHYLENE BETA-KETOESTER MONOMERS, POLYMERIZABLE COMPOSITIONS AND PRODUCTS FORMED THEREFROM | MACF1, MSMO1, ILK | CASP1 3843/4885ALDH1A1 1292/4885TSHR 4869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.