Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 2/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | PER2 | O15055 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15552907 | 0.90 | DDB1 (0.56) | DDB1CRBNHDAC8HDAC6KMT2A | |
| SCHEMBL6205439 | 0.80 | DDB1 (0.44) | DDB1CRBNHDAC8HDAC6KMT2A | |
| SCHEMBL4974543 | 0.79 | HDAC8 (0.47) | DDB1CRBNHDAC8HDAC6KMT2A | |
| SCHEMBL20329795 | 0.78 | KMT2A (0.47) | DDB1CRBNPER2KMT2AMEN1 | |
| SCHEMBL4791124 | 0.78 | KMT2A (0.47) | DDB1CRBNPER2KMT2AMEN1 | |
| SCHEMBL15319926 | 0.78 | ALDH1A1 (0.46) | DDB1CRBNHDAC8HDAC6KMT2A | |
| SCHEMBL15319529 | 0.77 | HDAC8 (0.48) | DDB1CRBNHDAC8HDAC6KMT2A | |
| SCHEMBL20334085 | 0.75 | KMT2A (0.44) | DDB1CRBNKMT2AMEN1NPC1 | |
| SCHEMBL22481526 | 0.75 | KMT2A (0.47) | DDB1CRBNHDAC8HDAC6KMT2A | |
| SCHEMBL29175230 | 0.75 | KMT2A (0.47) | DDB1CRBNHDAC8HDAC6PER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103102519-B | Rubber composition for tire tread and use its pneumatic tire | 横滨橡胶株式会社 | 2018-06-01 | — | — | CN | disclosed |
| EP-2004744-A1 | COMPOSITION INCLUDING MULTIPLE FUNCTIONALIZED POLYMERS | Bridgestone Corporation (JP) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007120797-A1 | COMPOSITION INCLUDING MULTIPLE FUNCTIONALIZED POLYMERS | BRIDGESTONE CORPORATION (JP) | 2007-10-25 | — | — | WO | disclosed |
| EP-0382205-A2 | Additive for thermosetting resins and thermosetting resin composition containing additive | NIPPON ZEON CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |