SCHEMBL5084592

SCHEMBL5084592

c1ccc(CC(CO[Si](c2ccccc2)(c2ccccc2)c2ccccc2)(CO[Si](c2ccccc2)(c2ccccc2)c2ccccc2)Cc2ccccc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.36
TAAR1 Q96RJ0 1/20 0.36
DUT P33316 1/20 0.36
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
LMNA P02545 1/20 0.34
CYP2D6 P10635 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
HIF1A Q16665 1/20 0.33
FDPS P14324 1/20 0.32
TSHR P16473 1/20 0.32
KCNA5 P22460 1/20 0.32
ADH1B P00325 1/20 0.31
ADH1C P00326 1/20 0.31
ADH1A P07327 1/20 0.31
ADH7 P40394 1/20 0.31
CALM1 P0DP23 1/20 0.31
TRPA1 O75762 1/20 0.31
IDO1 P14902 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5078189 0.92 SLC6A2 (0.35) SLC6A2TAAR1DUTCYP1A2CYP2C9
SCHEMBL5081544 0.89 SLC6A2 (0.33) SLC6A2TAAR1DUTLMNACYP2D6
SCHEMBL5080964 0.86 DUT (0.32) SLC6A2TAAR1DUTLMNACYP2D6
SCHEMBL5080896 0.81 SLC6A2 (0.38) SLC6A2TAAR1CYP1A2CYP2C9CYP2C19
SCHEMBL5081776 0.78 SLC6A2 (0.42) SLC6A2TAAR1CYP1A2CYP2C9CYP2C19
SCHEMBL5077245 0.76 SLC6A2 (0.34) SLC6A2TAAR1CYP1A2CYP2C9CYP2C19
SCHEMBL5080881 0.76 SLC6A2 (0.39) SLC6A2TAAR1CYP1A2CYP2C9CYP2C19
SCHEMBL8574799 0.75 DUT (0.39) DUT
SCHEMBL5082329 0.74 DUT (0.34) DUTSMN1; SMN2
SCHEMBL5081767 0.74 TAAR1 (0.38) SLC6A2TAAR1CYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US claimed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US claimed
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US disclosed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US disclosed