Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | KIF11 | P52732 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1653852 | 0.85 | HDAC8 (0.41) | HDAC8HDAC4HDAC2ACHEKIF11 | |
| SCHEMBL29013793 | 0.83 | HDAC8 (0.40) | HDAC8HDAC4HDAC2ACHEKIF11 | |
| SCHEMBL11754703 | 0.82 | PNMT (0.36) | KIF11PNMTIDO1TDO2 | |
| SCHEMBL598661 | 0.80 | KIF11 (0.49) | HDAC8HDAC4HDAC2ACHEKIF11 | |
| SCHEMBL21495044 | 0.79 | HDAC8 (0.41) | HDAC8HDAC4HDAC2ACHEKIF11 | |
| SCHEMBL926539 | 0.78 | ACHE (0.43) | HDAC8HDAC4HDAC2ACHEKIF11 | |
| SCHEMBL21654175 | 0.78 | HDAC8 (0.47) | HDAC8HDAC4HDAC2ACHEKIF11 | |
| SCHEMBL10431042 | 0.78 | HDAC4 (0.42) | HDAC8HDAC4HDAC2ACHEKIF11 | |
| SCHEMBL17449153 | 0.78 | ACHE (0.50) | HDAC8HDAC4HDAC2ACHEKIF11 | |
| SCHEMBL30705300 | 0.78 | PNMT (0.55) | ALDH1A1PNMTTSHRIDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1996600-A1 | METALLOCENE COMPOUNDS | Basell Polyolefine GmbH (DE) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007107448-A1 | METALLOCENE COMPOUNDS | BASELL POLYOLEFINE GMBH (DE) | 2007-09-27 | — | — | WO | disclosed |